AI Article Synopsis
- Between July 2009 and June 2011, rotavirus was found in 507 episodes of gastroenteritis in children under 3 years old in Gipuzkoa, Spain, with G-type determined in 90.3% of cases.
- During the 2010-2011 winter epidemic, G12 rotavirus became dominant, accounting for 65% of the cases, and showed a widespread impact across both rural and urban areas.
- The hospitalization rate for G12-infected children was significant, particularly in those under 2 years old, indicating that G12 may become a major rotavirus genotype in the future.
Article Abstract
Between July 2009 and June 2011, rotavirus was detected in 507 of 4597 episodes of acute gastroenteritis in children aged <3 years in Gipuzkoa (Basque Country, Spain), of which the G-type was determined in 458 (90·3%). During the annual seasonal epidemic of 2010-2011, the unusual G-type 12 was predominant, causing 65% (145/223) of cases of rotavirus gastroenteritis. All the G12 strains were clustered in lineage III and were preferentially associated with P-type 8. This epidemic was characterized by broad geographical distribution (rural and urban) and, over 7 months, affected both infants and children, the most frequently affected being children between 4 and 24 months. Of children with rotavirus G12, 16% required hospital admission, the admission rate in children aged <2 years being 20·7 cases/10 000 children. The sudden emergence and predominance of G12 rotaviruses documented in this winter outbreak suggest that they may soon become a major human rotavirus genotype.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151868 | PMC |
| http://dx.doi.org/10.1017/S0950268812001306 | DOI Listing |
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