We developed an efficient one-pot tandem carbamoyl chloride amination and palladium-catalyzed intramolecular urea cyclization, which furnished high-throughput access to imidazo[4,5-b]pyridine-2-one and related imidazo[4,5-c]pyridine-2-one ring systems. Moderate to excellent yields were reported.
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| http://dx.doi.org/10.1021/co300078f | DOI Listing |
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