Background: Positive behaviour support emphasises the impact of contextual variables to enhance participation, choice, and quality of life. This study evaluates a sequence for implementing changes to key contextual variables for 4 individuals. Interventions were maintained and data collection continued over a 3-year period.
Method: Functional assessments were conducted with 4 individuals with exceptionally severe challenging behaviours. Interventions were based on the multi-element model of behavioural support (LaVigna & Willis, 2005a). Dependent variables were behavioural ratings of (1) frequency, (2) episodic severity, (3) episodic management difficulty, and measures of (4) mental health status, and (5) quality of life. The intervention sequence was low arousal environment, rapport building, predictability, functionally equivalent skills teaching, and differential reinforcement strategies.
Results: Substantial reductions in target behaviours were observed, along with incremental improvement in mental health scores and quality-of-life scores.
Conclusion: The study demonstrates the efficacy of positive behaviour support for people with exceptionally severe behaviour in individually designed services.
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http://dx.doi.org/10.3109/13668250.2012.704982 | DOI Listing |
JAMA
January 2025
Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: T helper 2 (T2) cells and T helper 17 (T17) cells are CD4+ T cell subtypes involved in asthma. Characterizing asthma endotypes based on these cell types in diverse groups is important for developing effective therapies for youths with asthma.
Objective: To identify asthma endotypes in school-aged youths aged 6 to 20 years by examining the distribution and characteristics of transcriptomic profiles in nasal epithelium.
J Acquir Immune Defic Syndr
January 2025
Emory University Rollins School of Public Health, Department of Behavioral, Social, and Health Education Sciences.
Background: Pre-exposure prophylaxis for HIV prevention (PrEP) prescriptions in the U.S. have increased, yet only 15% of individuals assigned female at birth who could benefit from PrEP had received prescriptions as of 2022, with marked racial disparities.
View Article and Find Full Text PDFmSystems
December 2024
River Ecosystems Laboratory, Alpine and Polar Environmental Research Center, Ecole Polytechnique Fédérale de Lausanne (EPFL), Sion, Switzerland.
Unlabelled: Glacier-fed streams are permanently cold, ultra-oligotrophic, and physically unstable environments, yet microbial life thrives in benthic biofilm communities. Within biofilms, microorganisms rely on secondary metabolites for communication and competition. However, the diversity and genetic potential of secondary metabolites in glacier-fed stream biofilms remain poorly understood.
View Article and Find Full Text PDFmSystems
December 2024
Laboratory of Microbiology, Immunology, and Metabolism, Diprobio (Shanghai) Co., Limited, Shanghai, China.
Unlabelled: The gut microbiota plays a crucial role in infant health, with its development during the first 1,000 days influencing health outcomes. Understanding the relationships within the microbiota is essential to linking its maturation process to these outcomes. Several network-based methods have been developed to analyze the developing patterns of infant microbiota, but evaluating the reliability and effectiveness of these approaches remains a challenge.
View Article and Find Full Text PDFJ Am Coll Health
January 2025
Division of Thoracic Surgery and Interventional Pulmonology, Swedish Cancer Institute, Seattle, Washington, USA.
Objective: To use egocentric network analysis (ENA) to identify how the role of social networks relates to e-cigarette use among college fraternity members.
Participants: 212 fraternity members participated in this study.
Methods: Hierarchical logistic regression analyses assessed the relationship between egocentric network variables and ever use and current use of e-cigarettes.
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