Pheochromocytomas are rare neuroendocrine tumours of chromaffin tissues. They are catecholamine secreting tumours which cause severe hypertension and other systemic disturbances. Of all the causes of childhood hypertension, pheochromocytoma constitutes less than 1%. We report the case of a 12 years old child who presented with hypertensive encephalopathy, confirmed histologically to be secondary to pheochromocytoma, and cured with meticulous critical care and surgical resection.
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Pract Neurol
December 2024
Neurology Department, Creighton University, Omaha, Nebraska, USA.
Cureus
November 2024
Internal Medicine, Wellington Regional Medical Center, Wellington, USA.
Posterior reversible encephalopathy syndrome (PRES) is a neurologic condition defined by symptoms and imaging findings secondary to vasogenic edema in the brain. Even though not all hypertensive individuals will progress to PRES, high blood pressure is the most frequent risk factor associated with the condition. The pathophysiology of PRES is not clearly understood, but the most accepted proposed mechanism focuses on the brain's inability to regulate cerebral blood flow through constriction or dilation of vessels during extreme blood pressure.
View Article and Find Full Text PDFJ Assoc Physicians India
December 2024
Associate Professor, U N Mehta Institute of Cardiology and Research Centre, Ahmedabad, Gujarat, India.
A 62-year-old lady was referred with the diagnosis of hypertensive encephalopathy. She had episodes of paroxysms of hypertension while on the ventilator with normal saturations. She underwent a battery of tests to identify the cause of the paroxysms.
View Article and Find Full Text PDFQatar Med J
November 2024
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Introduction: Preeclampsia and eclampsia are hypertensive disorders of pregnancy associated with significant maternal and fetal morbidity and mortality. Posterior reversible encephalopathy syndrome (PRES) is a neurological complication observed in these conditions, yet its impact on fetomaternal outcomes remains underexplored. The aim of this study is to investigate the association between PRES and fetomaternal outcomes in women with preeclampsia and eclampsia.
View Article and Find Full Text PDFLancet Reg Health Am
January 2025
Department of Pathology, Hospital Universitario San Ignacio, Bogotá, Colombia.
Background: Children born to women with hypertension during pregnancy have a two to threefold increased risk of developing cognitive disorders compared to children born to women without hypertension. However, structural changes in the central nervous system of these children remain poorly understood. We aim to compare the brain histological findings from autopsies of neonates and fetuses born to women with and without hypertension during pregnancy.
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