AI Article Synopsis
- - The study investigates the vasorelaxant effects of C. nobile aqueous extract using isolated aortic rings from Wistar rats.
- - Three different doses of the extract (5, 10, and 20 mg/ml) were tested and showed a significant shift in the dose-response curve to norepinephrine after 30 minutes (p < 0.001).
- - The findings indicate that C. nobile aqueous extract has a notable vasorelaxant effect in vitro.
Article Abstract
This study aims to evaluate the in vitro vasorelaxant effect of C. nobile aqueous extract. We use aortic ring isolated from Wistar rats and aqueous C. nobile extract at doses of 5, 10 and 20 mg/ml. Incubation of aqueous C. nobile extract for 30 minutes produced a significant shift of the dose-response curve to norepinephrine (NE) (10(-8) to 10(-5) M) (p < 0.001). This study demonstrates that aqueous C. nobile extract possesses in vitro vasorelaxant effect.
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| http://dx.doi.org/10.3109/10641963.2012.712179 | DOI Listing |
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