Pediatric multifocal glioblastoma multiforme with fulminant course.

J Neurosci Rural Pract

Department of Neurosurgery, Dr. Achanta Lakshmipathi Neurosurgical Centre, Post Graduate Institute of Neurological Surgery, V.H.S Hospital, Taramani, Chennai, Tamil Nadu, India.

Published: May 2012

AI Article Synopsis

  • Glioblastoma multiforme (GBM) is the most prevalent type of primary malignant brain tumor, with pediatric cases being less common but having a better outlook than in adults.
  • A rare case of multifocal pediatric GBM is reported in a 5-year-old, who developed multiple lesions quickly after undergoing radiotherapy.
  • Further research is needed to explore the genetics, behavior, treatment, and outcomes of these uncommon tumors.

Article Abstract

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor. GBM in children is less common than in adults and has a better prognosis. Pediatric GBM is a rare entity, and a multifocal development in a pediatric GBM is much rarer. We report to you one such rare case of pediatric multifocal GBM in a 5-year-old child who developed rapidly increasing multiple lesions after radiotherapy. More studies are required to study the genetic analysis, tumor behavior, management and outcome of these rare tumors.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409990PMC
http://dx.doi.org/10.4103/0976-3147.98224DOI Listing

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