AI Article Synopsis

  • Researchers aimed to identify factors that influence mortality in patients with traumatic brain injury (TBI) using data from a national trauma project in Iran over five years.
  • A total of 2,274 TBI patients were analyzed, with a majority being male and the average age around 30; 16.9% of patients died from their injuries.
  • Key factors linked to mortality included age, Glasgow Coma Scale score, Injury Severity Score, blood pressure, and respiratory rate, highlighting the need for careful monitoring and management of these patients in emergency settings.

Article Abstract

Background: We aimed to determine factors associated with mortality rates in patients with traumatic brain injury (TBI).

Methods: Registered data of a national trauma project conducted in eight major cities in Iran during a five-year period were used. Patients with a TBI were identified and both univariate and multivariate analyses were performed.

Results: 2274 brain-injured patients including 1794 males (78.9%) were identified. The mean age of the patients was 30.1 ± 19.11 years. The age of 345 patients was less than 12, while 137 patients were older than 65. 383 patients (16.9%) died as a result of their injury. Univariate analysis showed a significant association between mortality and the following factors: age, sex, Glasgow Coma Scale (GCS), Injury Severity Score (ISS), systolic, diastolic and mean arterial blood pressure (BP), and respiratory rate (RR) (p<0.05).The logistic regression analysis revealed a statistically significant association between death and age (odds ratio [OR]=1.04), GCS (OR=0.59), ISS (OR=1.03), mean arterial BP (OR=0.71), and RR (OR=0.82) one-half hour after hospital arrival.

Conclusion: Our results demonstrated that age, GCS, ISS, BP, and RR as prognostic factors in patients with TBI indicate those that need special care during the initial management in the emergency department.

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