An extraovarian peritoneal serous carcinoma is characterised macroscopically by ovaries without pathology, histologically, however, by a serous carcinomatous structure in the pelvis, in an advanced tumour stage of usually marked peritoneal carcinomatosis. Extraovarian pelvic serous carcinomas are rarely described in literature. In our study on five patients with such carcinomas, laparotomy findings revealed peritoneal carcinomatosis as in advanced ovarian carcinomas, but without ovarian involvement. Histogenesis does not reveal any difference between the extraovarian mesothel, which is of Mullerian origin and the serous ovarian carcinoma. Therapy of extraovarian peritoneal carcinoma is similar to that of ovarian cancer with maximal tumour reduction and cisplatinum or carboplatinum containing chemotherapy. The prognosis is extremely unfavourable with little expectation of lengthy remission and survival rates are short. Extraovarian serous carcinomas deserve better recognition because they are underreported. They must be differentiated from malignant mesotheliomas, which are not of Mullerian origin.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1055/s-2008-1026362 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Presentation and Management of Highly Differentiated Follicular Carcinoma of Ovarian Origin With Gene Variants.
JCEM Case Rep
December 2024
Division of Endocrinology, Gerontology, and Metabolism, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Struma ovarii (SO) is a rare subtype of ovarian teratoma composed of more than 50% thyroid tissue. Extraovarian spread of SO, called peritoneal strumosis, was previously considered benign given the lack of histological malignant features. However, the 2020 World Health Organization Classification of Female Genital Tumors reclassified peritoneal strumosis as highly differentiated follicular carcinoma of ovarian origin (HDFCO), highlighting its low-grade malignant potential.
View Article and Find Full Text PDFKrukenberg tumours: which patients should be considered for surgery?-a narrative literature review.
Transl Cancer Res
October 2024
Department of Gynaecology Oncology, Churchill Hospital, Oxford University Hospitals National Health Service (NHS) Foundation Trust, Oxford, UK.
Background And Objective: Krukenberg tumours (KTs) are metastatic signet ring cell (SRC) adenocarcinomas of the ovary, arising from the stomach in most cases (70%). Other common primary sites are the colon, appendix and breast. The use of the term "Krukenberg tumour" is inconsistent in the literature which makes data interpretation difficult.
View Article and Find Full Text PDFLarge descending colon alveolar soft part sarcoma with ASPL-TFE3 fusion gene: Case report and review of the literature.
Int J Surg Case Rep
November 2024
Department of General Surgery-colorectal Surgery, Cleveland Clinic, Abu Dhabi, United Arab Emirates.
Introduction: ASPS is a rare, soft tissue tumor which represents 0.2-1 % of soft tissue sarcomas. A characteristic nonreciprocal translocation is found in nearly all cases.
View Article and Find Full Text PDFSTK11 (LKB1) immunohistochemistry is a sensitive and specific marker for STK11 adnexal tumours.
Histopathology
November 2024
Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Article Synopsis
- - STK11 adnexal tumours are rare malignant neoplasms associated with Peutz-Jeghers syndrome, primarily arising from para-adnexal soft tissues and potentially affecting the fallopian tube and ovary; diagnosis currently involves identifying STK11 mutations.
- - Researchers conducted immunohistochemistry (IHC) on 122 tumours, including 17 STK11 adnexal tumours and 105 lookalikes; results showed that STK11 adnexal tumours had complete loss of STK11 protein expression, while other tumour types generally retained it.
- - The study concludes that STK11 serves as a sensitive and specific marker for distinguishing STK11 adnexal tumours
Rare Broad Ligament Cavernous Hemangioma Mimicking Advanced Endometriosis: A Case Report.
Reprod Sci
November 2024
Department of Obstetrics and Gynecology, Lenox Hill Hospital- Northwell Health/Zucker School of Medicine, New York, NY, USA.
Cavernous hemangioma within the female genital tract is an extremely rare pathology, characterized by irregular vascular spaces containing blood or thrombus. We present a unique case of a 42-year-old primiparous woman who presented with typical endometriosis symptoms such as dysmenorrhea, dyspareunia, and heavy menstrual bleeding. The patient also experienced complex postpartum symptoms, which were misdiagnosed as cholecystitis and retained placental products.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!