AI Article Synopsis
- This review focuses on small intestine serine proteases, highlighting their importance in digestion and overall gastrointestinal function.
- It discusses their structural features, where they are located in the cells, and how their activity is regulated, providing a comprehensive understanding of their role.
- Serine proteases are crucial for various physiological processes, including digestion, tissue renewal, muscle function, hormone regulation, and intestinal defense mechanisms.
Article Abstract
In this review we present data about small intestine serine proteases, which are a considerable part of the proteolytic apparatus in this major part of the gastrointestinal tract. Serine proteases of intestinal epitheliocytes, their structural-functional features, cellular localization, physiological substrates, and mechanisms of activity regulation are examined. Information about biochemical and functional properties of serine proteases is presented in a common context with morphological and physiological data, this being the basis for understanding the functional processes taking place in upper part of the intestine. Serine proteases play a key role in the physiology of the small intestine and provide the normal functioning of this organ as part of the digestive system in which hydrolysis and suction of food substances occur. They participate in renewal and remodeling of tissues, retractive activity of smooth musculature, hormonal regulation, and defense mechanisms of the intestine.
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| http://dx.doi.org/10.1134/S0006297912080032 | DOI Listing |
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