In this article the authors discuss the issues related to assessment of activity and severity of sarcoidosis, course and radiographic manifestations of this disease. Problems in defining of different forms of sarcoidosis resulted in suggestion of new version of classification.
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Global health inequalities in the burden of interstitial lung disease and pulmonary sarcoidosis from 1990 to 2021.
BMC Public Health
November 2024
The First School of Clinical Medicine, Lanzhou University, No. 222 Tianshui Road (South), Cheng-Guan District, Lanzhou City, 730030, China.
Background: Interstitial lung disease and pulmonary sarcoidosis remain serious medical problems worldwide. This study aims to assess the global burden and health inequalities of interstitial lung disease and pulmonary sarcoidosis between 1990 and 2021.
Methods: Data on disability-adjusted life years (DALYs) due to interstitial lung disease and pulmonary sarcoidosis were obtained from the Global Burden of Diseases, Injuries and Risk Factors Study 2021.
[Medical clinical diagnostics for indoor mould exposure - Update 2023 (AWMF Register No. 161/001)].
Pneumologie
October 2024
Labor Dr. Wisplinghoff.
This article is an abridged version of the updated AWMF mould guideline "Medical clinical diagnostics in case of indoor mould exposure - Update 2023", presented in July 2023 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with German and Austrian scientific medical societies, and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established. There is no evidence for a causal relationship between moisture/mould damage and human diseases, mainly because of the ubiquitous presence of fungi and hitherto inadequate diagnostic methods.
View Article and Find Full Text PDFEffect of exercise on cluneal nerve entrapment neuropathy: a case report.
J Med Case Rep
July 2024
Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Suleyman Demirel University, Isparta, Turkey.
Article Synopsis
- Low back pain is a significant issue in clinics, often involving neuropathic pain, and the superior cluneal nerve entrapment syndrome is a key but underdiagnosed cause that requires careful diagnosis.
- A 22-year-old male patient with various health issues was evaluated and prescribed a specific exercise program focusing on lumbar stabilization and gluteal strengthening to address his low back pain.
- The study highlights that proper diagnosis and targeted exercises can effectively aid in the treatment of cluneal nerve entrapment syndrome, which is often a common factor in chronic low back pain cases.
Temporal relationship between sarcoidosis and malignancies in a nationwide cohort of 1942 patients.
Postgrad Med J
November 2024
Department of Autoimmune Diseases, ICMiD, Hospital Clinic, Barcelona, 08036, Spain.
Purpose: To investigate the phenotype of sarcoidosis according to the time when a malignancy is diagnosed (preexisting to the diagnosis of sarcoidosis, concomitant, or sequential) and to identify prognostic factors associated with malignancies in a large cohort of patients with sarcoidosis.
Methods: We searched for malignancies in the SARCOGEAS cohort, a multicenter nationwide database of consecutive patients diagnosed with sarcoidosis according to the ATS/ESC/WASOG criteria. Solid malignancies were classified using the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) nomenclature, and hematological malignancies using the 2016 WHO classification.
Clinical trials in pulmonary sarcoidosis; what is needed, what is happening and what is next?
Curr Opin Pulm Med
September 2024
ILD Center of Excellence, member of European Reference Network-Lung, St Antonius Hospital, Nieuwegein, The Netherlands.
Purpose Of Review: There is a clinical unmet need to improve treatment for patients with pulmonary sarcoidosis. Both retrospective and prospective drug trials are hampered by the fact that patients with sarcoidosis are characterized by a heterogeneous presentation and disease course. In this review, an overview is given of different drug trials in pulmonary sarcoidosis with an emphasis on different primary endpoints and the problems related to them.
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