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| http://dx.doi.org/10.4269/ajtmh.2012.12-0108 | DOI Listing |
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Strongyloides hyperinfection and disseminated infections are usually associated with immunosuppression; these severe manifestations occur in a minority of cases. The use of immunosuppressants such as corticosteroids and Baricitinib for treating COVID-19 pneumonia can be responsible for patients' immunosuppression and cause Strongyloides hyperinfection syndrome. The chance increases when the patient belongs to countries or regions where chronic infection with Strongyloides is more prevalent.
View Article and Find Full Text PDFParasitic Infections in Pulmonary and ICU Patients: Presentation, Diagnosis, and Treatment.
Chest
November 2024
Infectious Diseases Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX. Electronic address:
Article Synopsis
- Parasitic infections in the U.S. primarily affect immigrants and travelers, often leading to delayed diagnoses by physicians unfamiliar with these diseases.
- Nearly 2,000 cases of imported malaria occur annually, with severe symptoms that can mimic bacterial sepsis, and treatment requires careful management to improve survival.
- Strongyloidiasis, endemic in warm regions, can stay dormant for years and worsen if corticosteroids are used, while other infections like cystic echinococcosis and paragonimus present with specific respiratory symptoms and are found in various global regions, including parts of North America.
High prevalence of anti-Strongyloides antibody in SARS-CoV-2-infected human sera in a Thai hospital: Rapid serological screening.
J Infect Public Health
August 2024
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand; Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Article Synopsis
- - COVID-19, caused by SARS-CoV-2, can lead to severe lung issues and systemic dysfunction, prompting the use of immunosuppressive treatments that risk worsening existing infections like strongyloidiasis.
- - A study in Thailand found a significant prevalence of anti-Strongyloides IgG antibodies in 39.4% of 297 COVID-19 patients, suggesting a potential relationship between these infections and COVID-19.
- - Researchers recommend using a rapid immunochromatographic test for strongyloidiasis screening in critically ill COVID-19 patients, coupled with immediate treatment to prevent severe complications in those at risk.
Strongyloides stercoralis hyperinfection presenting pneumatosis intestinalis and acute respiratory distress syndrome after treatment for COVID-19.
Rev Esp Enferm Dig
October 2024
Medical Checkup, Naha City Hospital, Japan.
Article Synopsis
- CT scans revealed pneumatosis intestinalis, and his respiratory condition worsened as Strongyloides stercoralis was found, leading to a diagnosis of hyperinfection syndrome and acute respiratory distress syndrome.
- The late treatment with ivermectin was unsuccessful, and the patient ultimately died from multiple organ failure, emphasizing the need to monitor for chronic strongyloidiasis in COVID-19 patients in endemic regions who are on steroids.
Insights into parasites and COVID-19 co-infections in Iran: a systematic review.
Trans R Soc Trop Med Hyg
June 2024
Zoonoses Research Center, Ardabil University of Medical Sciences, Ardabil 56189-53141, Iran.
Background: It is well-documented that using immunosuppressive drugs such as corticosteroids or cytokine blockers in treating coronavirus disease 2019 (COVID-19) increases the risk of co-infections. Here we systematically summarized the cases of COVID-19-associated parasitic infections (CAPIs) in Iran.
Methods: From 19 February 2020 to 10 May 2023, all studies on Iranian patients suffering from CAPIs were collected from several databases using a systematic search strategy.
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