The authors developed a method for studying the whole arterial system, except for the coronary arteries, by means of ultrasonic techniques. It was based on the conception of the generalized nature of atherosclerosis presuming the existence of some specific types of the process which may be classified into 5 categories (according to DeBakey) depending on the main focus of distribution of the disease. The method was named pan-arterial ultrasonography. It includes a series of ultrasonic examinations performed by means of Doppler's ultrasonic scanning apparatus operating in B-regimen with various transducers for determining the arterial blood flow and imaging the various arterial segments. The authors examined successfully 716 patients by the method.
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ACS Chem Neurosci
January 2025
School of Medicine, Shanghai University, Shanghai 200444, China.
Noninvasive imaging of β-amyloid is pivotal for the early diagnosis of Alzheimer's disease (AD). While single imaging methods have been extensively studied for detecting Aβ over the past decade, dual-modal probes have received scant attention. In this study, we synthesized and assessed a series of half-curcumin probes, among which demonstrated a high affinity and selectivity for Aβ aggregates.
View Article and Find Full Text PDFAdv Clin Chem
January 2025
Department of Obstetrics and Gynecology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address:
Preeclampsia (PE), a pregnancy-related syndrome, has motivated extensive research to understand its pathophysiology and develop early diagnostic methods. 'Omic' technologies, focusing on genes, mRNA, proteins, and metabolites, have revolutionized biological system studies. Urine emerges as an ideal non-invasive specimen for omics analysis, offering accessibility, easy collection, and stability, making it valuable for identifying biomarkers.
View Article and Find Full Text PDFJ Am Soc Echocardiogr
January 2025
Cardiology Clinic, University Center Serbia, Medical School, University Clinical Center Serbia, University of Belgrade, Serbia.
Background: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity including patients with different phenotypes of near normal, normal, and supernormal left ventricular (LV) function.
Objectives: To assess the value of resting LV elastance (also known as force) with transthoracic echocardiography (TTE) to identify HFpEF phenotypes.
Methods: In a prospective, observational, multicenter study, 2380 HFpEF patients were recruited from July 2016 to May 2024.
Food Chem
December 2024
INRAE, OPAALE, 35044 Rennes, France. Electronic address:
Understanding lipid digestion is crucial for promoting human health. Traditional methods for studying lipolysis face challenges in sample representativeness and pre-treatment, and cannot measure real-time lipolysis in vivo. Thus, non-invasive techniques like magnetic resonance imaging (MRI) need to be developed.
View Article and Find Full Text PDFUltrasonics
January 2025
Department of Robotics and Mechatronics, AGH University of Krakow, 30-059 Krakow, Poland. Electronic address:
Ultrasound shear wave elastography (SWE) is widely used in clinical applications for non-invasive measurements of soft tissue viscoelasticity. The study of tissue viscoelasticity often involves the analysis of shear wave phase velocity dispersion curves, which show how the phase velocity varies with frequency or wavelength. In this study, we propose an alternative method to the two-dimensional Fourier transform (2D-FT) and Phase Gradient (PG) methods for shear wave phase velocity estimation.
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