Pathology of 4 cases of serologically verified HIV infection is described. In 3 cases the disease developed against the background of previous pathologic processes that in one way or another influenced the pathologic picture. Only general characteristics of the HIV pathology are given in this report obtained by routine methods. Detailed investigation of changes in different organs and systems will be continued. Morphological signs of the immunodeficiency manifesting mainly in more or less atrophy of lymphoid tissue were found in all cases examined. Though features specific for HIV infection are not established in the literature, the complex of the above changes allows one to suspect HIV infection and in case of serologic confirmation to formulate a pathologic diagnosis. The 4th case can be regarded as an earlier stage of HIV infection as well as an example of a therapeutically produced pathomorphosis.
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