Intramural metastasis to the stomach (IMMS) from carcinoma esophagus, excluding direct invasion and spread to the stomach, is relatively uncommon. Diagnosis of IMMS is based on histological criteria, and it is associated with poor prognosis (Takubo et al. Cancer 65:1816-1819, 1990]. We report two patients of SCC oesophagus in whom intramural metastasis to stomach has occurred.
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http://dx.doi.org/10.1007/s12262-011-0248-z | DOI Listing |
Cancer Metastasis Rev
December 2024
Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
The field of chimeric antigen receptor (CAR) T-cell therapy has grown from a fully experimental concept to now boasting a multitude of treatments including six FDA-approved products targeting various hematologic malignancies. Yet, along with their efficacy, these therapies come with side effects requiring timely and thoughtful interventions. In this review, we discuss the most common toxicities associated with CAR T-cells to date, highlighting risk factors, prognostication, implications for critical care management, patient experience optimization, and ongoing work in the field of toxicity mitigation.
View Article and Find Full Text PDFAdv Mater
December 2024
Institute of Marine Science and Technology, Shandong University, Qingdao, 266237, China.
Exosomes, functional biomarkers involved in cancer progression, have gained widespread attention for promoting tumor formation, growth, and metastasis. Current bulk exosome detections in bodily fluids enable cancer functional analysis, but average secretion levels from cell populations, losing parent cell information and ignoring exosome heterogeneity from diverse cell subgroups, necessitating an effective platform for analyzing single-cell exosome functional heterogeneity. Here, a high-throughput platform is presented, capable of efficient single-cell isolation and multi-color exosome phenotype analysis, as well as quantifying trace exosomes secreted by single cells.
View Article and Find Full Text PDFRadiol Case Rep
February 2025
Head and Neck Surgery Unit, ENT Department of Geneva University Hospital, Gabrielle-Perret-Gentil 4, 1205 Genève, Switzerland.
A 58-year-old male with squamous cell carcinoma of the floor of mouth underwent surgical planning for tumor resection and floor of mouth reconstruction. Unexpectedly, preoperative cervico-thoracic computed tomography (CT) indicated possible right ventricular intramural thrombosis, prompting initiation of unfractionated heparin. Follow-up echocardiography revealed no thrombus reduction, raising concerns of intracardiac metastasis.
View Article and Find Full Text PDFDiscov Oncol
November 2024
Haematology-Oncology Unit, Department of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Cancer Metastasis Rev
November 2024
Division of Intramural Research, National Institute of Environmental Health Science, National Institute of Health, Research Triangle Park, NC, USA.
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