Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437781 | PMC |
| http://dx.doi.org/10.1136/gutjnl-2012-301994 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
HCCR-1 is a Novel Prognostic Indicator for Gastric Cancer and Promotes Cell Proliferation.
J Cancer
June 2019
Department of Gastrointestinal Surgery , Nantong University Affiliated Hospital, Nantong 226001, Jiangsu, China.
The role of the human cervical cancer oncogene () in the development of various tumors has been elucidated; however, its expression and function in gastric cancer remains largely unknown. Accordingly, the expression of HCCR-1 and epidermal growth factor (EGF) were detected in paired gastric cancer tissues and cell lines by western blotting (WB) and immunohistochemistry (IHC). Furthermore, the correlations between HCCR-1 expression in 209 gastric cancer tissues and the clinicopathological features and disease prognosis were analyzed.
View Article and Find Full Text PDFHuman cervical cancer oncogene-1 over expression in colon cancer and its clinical significance.
Int J Clin Exp Med
March 2015
Department of General Surgery, Qilu Hospital, Shandong University Jinan 250012, Shandong, China.
Objective: This study was to explore the expression of human cervical cancer oncogene-1 (HCCR-1) in colon cancer and its clinical significance.
Methods: RT-PCR, immunohistochemistry and Western blot assay were employed to detect HCCR-1 expression in 152 colon cancers, 43 adjacent non-cancerous tissues and 37 normal tissues. In addition, immunohistochemistry was done to detect CEA in colon cancers.
Combined analysis of AFP and HCCR-1 as an useful serological marker for small hepatocellular carcinoma: a prospective cohort study.
Dis Markers
July 2012
Department of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hepatocellular carcinoma (HCC) is one of the most frequent malignant tumors in the world. The only serological marker widely used for the diagnosis of HCC is alpha-fetoprotein (AFP). Despite that AFP is widely used for the diagnosis of HCC, it has a limit as a serological marker due to its low sensitivity and specificity.
View Article and Find Full Text PDF[Preparation and characterization of monoclonal antibody against HCCR protein].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
October 2011
Institute of Radiation Medicine Academy of Military Medical Science, Beijing, China.
Aim: Preparation of monoclonal antibody (mAb) to HCCR, which is a candidate biomarker for human hepatocellular carcinoma (HCC).
Methods: The recombinant protein HCCR-1(167-360); was expressed and was used as immunogen to immunize mouse for generation of mAb against HCCR. The protein Ep-HCCR, which displayed a epitope of HCCR, was also expressed and purified to use to detect serum antibody titer and to screen the positive clones of hybridmas.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!