AI Article Synopsis
- A new method for transforming N-substituted tryptophols using Lewis acid catalysis was developed, involving a cascade dearomatization process.
- This method utilizes a Michael addition reaction, leading to the creation of furoindoline derivatives.
- The approach is versatile, successfully producing compounds with a quaternary carbon center in good yields.
Article Abstract
Lewis acid-catalyzed cascade dearomatization of N-substituted tryptophols via Michael addition reaction was developed. The generality of the method has been demonstrated by the synthesis of versatile furoindoline derivatives with a quaternary carbon center in good yields.
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| http://dx.doi.org/10.1039/c2ob26139a | DOI Listing |
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