AI Article Synopsis
- A 47-year-old man was diagnosed with limited-disease small cell lung cancer and began treatment with chemotherapy and radiotherapy, leading to a partial response.
- After treatment, he received prophylactic cranial irradiation (PCI), but local recurrence occurred, prompting the use of amrubicin (AMR), which resulted in stable disease after two courses.
- Unfortunately, after the third course of AMR, he was hospitalized with severe headache and consciousness issues, ultimately diagnosed with carcinomatous meningitis, highlighting the challenges of managing this cancer despite preventive measures.
Article Abstract
A 47-year-old man was diagnosed with limited-disease small cell lung cancer. Treatment was initiated with concurrent chemotherapy and radiotherapy. A partial response was achieved, and prophylactic cranial irradiation (PCI) was administered. Local recurrence was identified on follow-up and treated with amrubicin (AMR). After two courses of AMR, a state of stable disease was achieved and AMR treatment was continued. After the third course of AMR, the patient was urgently hospitalized suffering from a headache and disturbance of consciousness, and a diagnosis of carcinomatous meningitis was made. This case report concerns a case of carcinomatous meningitis despite PCI during treatment with AMR.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402736 | PMC |
| http://dx.doi.org/10.3892/ol.2012.725 | DOI Listing |
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