Aortic aneurysms remain a significant source of morbidity and mortality after use of Dacron(®) patch aortoplasty to repair coarctation of the aorta: results from a single center.

Pediatr Cardiol

Department of Pediatrics, Division of Cardiology, Medical College of Wisconsin, Children's Hospital of Wisconsin, Herma Heart Center, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA.

Published: February 2013

AI Article Synopsis

  • * A study of 63 patients treated with Dacron(®) patch aortoplasty found that nearly half (47%) developed aneurysms, with a notable 31% of those experiencing spontaneous ruptures, resulting in high mortality rates.
  • * The findings underscore the importance of regular imaging (CT or MRI) every 5 years for all patients who've had coarctation repair, with more frequent assessments recommended for those treated with Dacron(®) due to the ongoing risk of complications.

Article Abstract

Aortic aneurysm formation after coarctation repair is a serious and life-threatening complication. Repairs using synthetic materials such as Dacron(®) may carry the highest risk of aneurysm formation and rupture. The authors sought to determine the prevalence of aneurysm formation in patients who previously underwent coarctation repair using Dacron(®) patch aortoplasty at their institution. Between 1977 and 1994, 63 patients underwent isolated coarctation repair using Dacron(®) patch aortoplasty. Aneurysms were defined as an aortic dimension 1.5 times that of the aorta at the level of the diaphragm as shown by angiography, computed tomography (CT) scan, or magnetic resonance imaging (MRI). Of 61 early survivors, 29 (47 %) experienced an aneurysm in the area of previous repair. Nine patients (31 %) had spontaneous rupture of the aneurysm, which caused death in seven cases. Elective or emergent aneurysm repair was performed for 20 patients without complication, and 2 patients are being monitored at this writing. The mean interval from patch placement to aneurysm repair was 15 years (range, 4-27 years). Overall freedom from the development of an aortic aneurysm was 97 % at 5 years, 90 % at 10 years, 69 % at 20 years, and 42 % at 25 years. After repair of coarctation using Dacron(®) patch aortoplasty, the risk for aneurysm formation in the area of repair and death from rupture is extremely high. Therefore, in accordance with the 2008 American Heart Association/American College of Cardiology (AHA/ACC) guidelines, all patients with repaired aortic coarctation should undergo either CT or MRI imaging at least every 5 years to assess for aortic aneurysm formation. More frequent imaging should be obtained for patients previously repaired with Dacron(®) patch aortoplasty.

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Source
http://dx.doi.org/10.1007/s00246-012-0442-1DOI Listing

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