Before integrating nurse practitioners into a critical care environment, it is important to understand the infrastructure and support necessary to guide clinical practice and utilization. NP practice teams should be structured with a cohesive strategy to provide 24/7 patient coverage and consistency in evidence-based care.
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How I Do It: Nurse Practitioners and Physician Assistants: Building a Team and Optimizing Practice in the Medical ICU.
Chest
November 2024
University of Illinois Chicago, College of Nursing.
The integration of Nurse Practitioners (NPs) and Physician Assistants (PAs) in the Medical Intensive Care Unit (MICU) is becoming increasingly vital due to the rising number of critically ill patients and the shortage of board-certified intensivists. Successful recruitment and utilization of NPs and PAs into the MICU setting require a unique understanding of potential variations of the scope of practice based on state law and educational backgrounds, as well as the implementation of best practices around training and leadership support. The purpose of this article is to review the best strategies for creating a MICU team with NPs and PAs.
View Article and Find Full Text PDFNurse Practitioners (NPs) as Game Changers in Tanzania Health Delivery System: Lessons Learnt from Fujita Bantane Hospital in Japan.
Asian J Neurosurg
December 2024
Department of Neurosurgery, Hospital Sungai Buloh, Selangor, Malaysia.
Shortage of physicians/doctors in the primary health care system has been evidenced in various countries. Among other things, these countries deployed nurse practitioners (NPs) in the health care delivery system to address this shortage. Countries in America, Europe, and Asia use NPs to address physicians/doctors shortage in the primary health care delivery systems.
View Article and Find Full Text PDFMachine learning-based model for predicting the occurrence and mortality of nonpulmonary sepsis-associated ARDS.
Sci Rep
November 2024
Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210016, Jiangsu, China.
Objective: The objective was to establish a machine learning-based model for predicting the occurrence and mortality of nonpulmonary sepsis-associated ARDS.
Methods: 80% of sepsis patients selected randomly from the MIMIC-IV database, without prior pulmonary conditions and with nonpulmonary infection sites, were used to construct prediction models through machine learning techniques (including K-nearest neighbour, extreme gradient boosting, support vector machine, deep neural network, and decision tree methods). The remaining 20% of patients were utilized to validate the model's accuracy.
Prolonged Retention of Albumin Nanoparticles Alleviates Renal Ischemia-Reperfusion Injury through Targeted Pyroptosis.
ACS Appl Mater Interfaces
November 2024
Department of Nephrology, Huai'an Key Laboratory of Chronic Kidney Disease, The Affiliated Huai'an Hospital of Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an 223002, China.
Acute kidney injury (AKI) represents a prevalent and complex clinical event, characterized by irreversible damage to renal tubular epithelial cells and high intensive care unit (ICU) admission rates and mortality. The kidneys are highly susceptible to oxidative stress, inflammation, pyroptosis, and programmed cell death. Pyroptosis poses a significant risk, exacerbating the damage and inflammation of renal tubular cells.
View Article and Find Full Text PDFBiomimetic Nanomodulator Regulates Oxidative and Inflammatory Stresses to Treat Sepsis-Associated Encephalopathy.
ACS Nano
October 2024
Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmaceutical Sciences, National Key Laboratory of Innovative Immunotherapy, Shanghai Jiao Tong University, Shanghai 200240, China.
Sepsis-associated encephalopathy (SAE) is a devastating complication of sepsis, affecting approximately 70% of patients with sepsis in intensive care units (ICU). Although the pathophysiological mechanisms remain elusive, sepsis is typically accompanied by systemic inflammatory response syndrome (SIRS) and hyper-oxidative conditions. Here, we introduce a biomimetic nanomodulator (mAOI NP) that specifically targets inflammation site and simultaneously regulates oxidative and inflammatory stresses.
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