Making a noisy gene: HDACs turn up the static.

Mol Cell

Howard Hughes Medical Institute, Department of Biomedical Engineering and Center for BioDynamics, Boston University, Boston, MA 02215, USA.

Published: July 2012

In this issue of Molecular Cell, Weinberger et al. (2012) find that particular histone deacetylases (HDACs) regulate distinct stages of transcription, implicating chromatin dynamics in the generation of gene-specific noise within populations of genetically identical cells.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417138PMC
http://dx.doi.org/10.1016/j.molcel.2012.07.008DOI Listing

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