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TccP4: a novel effector identified in the strain 1551-2 required for attaching and effacing lesion formation on infected Nck-null cells.
Microbiol Spectr
January 2025
Instituto de Biociências, Universidade Estadual Paulista (UNESP), Botucatu, Brazil.
is a pathogen that causes sporadic cases and outbreaks of diarrhea. The main virulence feature of this bacterium is the attaching and effacing (AE) lesion formation on infected intestinal epithelial cells, which is characterized by the formation of pedestal-like structures that are rich in F-actin. The Brazilian 1551-2 strain can recruit F-actin using both the Nck-dependent and the Nck-independent pathways, the latter of which uses an adaptor protein named Tir-cytoskeleton coupling protein (TccP/EspF).
View Article and Find Full Text PDFDistribution of Tunisian beet wild relatives ( sp.) according to morphological characteristics and eco-geographical origin.
Heliyon
January 2025
Laboratory of Plant Protection, National Institute of Agronomic Research of Tunisia, University of Carthage, Rue Hedi Karray, 2049, El-Menzah, Tunisia.
subsp. (L.) Arcang.
View Article and Find Full Text PDFNovel NOTCH3 mutation c.1564 T > A (p.Cys522Ser) presenting with early-onset Parkinsonism and white matter lesions.
Clin Park Relat Disord
January 2025
Cerebrovascular Unit Fondazione IRCCS Istituto Neurologico Carlo Besta Milan Italy.
CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a hereditary small vessel disease caused by mutations in the NOTCH3 gene, characterized by recurrent strokes, cognitive decline, and psychiatric symptoms. This report presents a novel NOTCH3 c.1564 T > A (p.
View Article and Find Full Text PDFRelationship Between Subjectively Assessed Physical Activity (GPAQ) and Quality of Life (WHOQOL-BREF) of Aging Employees in JIPMER, Puducherry: A Cross-Sectional Analytical Study.
Indian J Occup Environ Med
December 2024
College of Nursing, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Background: Physical activity appears to be one of the most important strategies for preventing physical and mental disorders. Regular physical activity (PA) may prolong life and appears to be a preventative measure against genetic and molecular aging.
Aim: To find the relationship between aging adults' quality of life (QOL) and PA.
Fetal hematological phenotypes of various hemoglobinopathies and demonstration of embryonic hemoglobins on capillary electrophoresis: a large cohort data from prenatal screening program.
Diagnosis (Berl)
January 2025
Faculty of Associated Medical Sciences, Centre for Research and Development of Medical Diagnostic Laboratories, Khon Kaen University, Khon Kaen, Thailand.
Objectives: This study reported a large cohort of fetal blood analysis of various hemoglobinopathies.
Methods: A total of 371 fetal blood specimens were recruited. Complete blood count and hemoglobin (Hb) analysis using capillary electrophoresis were performed.
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