During the 1990s, an epidemic of B:4 Neisseria meningitidis infections affected Brazil. Subsequent increase in C:4 disease suggested B → C capsular switching. This study identified B → C switches within the sequence type 32 complex. Substantial disease related to capsular switching emphasizes the need for surveillance of circulating meningococcal strains to optimize disease control.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414017 | PMC |
| http://dx.doi.org/10.3201/eid1808.111344 | DOI Listing |
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