Membrane protein distribution in composite polymer-lipid thin films.

Chem Commun (Camb)

Swiss Nanoscience Institute, University of Basel, Klingelbergstr. 82, 4056 Basel, Switzerland.

Published: September 2012

We present a model system to demonstrate that the positioning of biomolecules (membrane proteins) in a nonnative, complex thin film environment can be regulated by the phase behavior of film components. Partial separation between an amphiphilic polymer and a lipid drives the protein to a fluid phase, mechanically more similar to a cellular bilayer.

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http://dx.doi.org/10.1039/c2cc32851hDOI Listing

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