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[Extramedullary hematopoiesis, a rare complication of sickle cell disease: A six-case series and literature review].
Rev Med Interne
January 2025
Service de médecine interne, centre national de référence des syndromes drépanocytaires majeurs de l'adulte, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France; Inserm U1163, laboratoire « Mécanismes cellulaires et moléculaires des désordres hématologiques et implications thérapeutiques », institut Imagine, université Paris-Cité, 75015 Paris, France; Laboratoire d'Excellence GR-Ex, 75015 Paris, France; Faculté de santé, université Paris-Cité, 75006 Paris, France. Electronic address:
Introduction: Extramedullary hematopoiesis (EMH) is very rarely described during sickle cell disease (SCD). Our aim was to describe six cases of EMH occurring in adult SCD patients and to conduct a literature review.
Methods: Retrospective, descriptive, and monocentric study, identifying all cases of EMH recorded in our cohort of adult SCD patients, up to April 2024.
Application of integrated omics in aseptic loosening of prostheses after hip replacement.
Mol Med Rep
March 2025
Department of Orthopedics, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Aseptic loosening (AL) of artificial hip joints is the most common complication following hip replacement surgery. A total of eight patients diagnosed with AL following total hip arthroplasty (THA) undergoing total hip replacement and eight control patients diagnosed with avascular necrosis of femoral head (ANFH) or femoral neck fracture undergoing THA were enrolled. The samples of the AL group were from synovial tissue surrounding the lining/head/neck of the prosthesis, and the samples of the control group were from the synovium in the joint cavity.
View Article and Find Full Text PDFLong-term results of short stem total hip arthroplasty in patients with osteonecrosis of the femoral head.
Arch Orthop Trauma Surg
December 2024
Department of Orthopaedic Surgery, Uthumphon Phisai Hospital, Uthumphon Phisai District, Sisaket Province, 33120, Thailand.
Introduction: Short stem total hip arthroplasty (THA) is an alternative to conventional stem, designed to facilitate minimal-invasive surgery, physiological loading and preserve bone stock. However, there is insufficient evidence of the long-term outcomes in patients with osteonecrosis of the femoral head (ONFH). This study aims to analyze the clinical and radiographic results with a minimum follow-up of 10 years.
View Article and Find Full Text PDFIntegrating manual therapy into conservative management of a patient with bilateral femoral head avascular necrosis: A case report with a 2-year follow up.
J Bodyw Mov Ther
October 2024
The George Washington University Hospital, Musculoskeletal Radiology, Washington, DC, 20037, USA.
Article Synopsis
- A case report outlines the effects of physical therapy on a 56-year-old male with bilateral femoral head avascular necrosis (AVN), a condition that limits hip function.
- The patient received various interventions, including manual therapy and therapeutic exercises, which led to significant improvements in pain and functional scores after eight sessions over 10 weeks.
- The findings suggest that early physical therapy can enhance independence for AVN patients and possibly decrease the likelihood of needing surgery, indicating a need for more research on effective treatment strategies.
Total hip arthroplasty in patients under 35 years: a systematic review of the last 2 decades studies.
Hip Int
January 2025
Operative Research Unit of Orthopaedic and Trauma Surgery, Campus Bio-Medico University Hospital, Rome, Italy.
Background: Patients with total hip arthroplasty (THA) under the age of 35 represent a small and heterogeneous group of 1% of all THA performed. This systematic review aims to analyse the diagnosis, implant type, complications, and long-term results in these patients.
Methods: A search was performed on PubMed, Scopus, and Cochrane Library up to 31 July 2023.
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