AI Article Synopsis
- A study of 66 patients with untreated infiltrative tuberculosis aimed to optimize the assessment of the inflammatory process by analyzing acute phase protein levels.
- The research looked at clinical and radiological data dynamics, along with the timeline for achieving abacillarization (reduction of bacteria) after three months of anti-tuberculosis therapy.
- It was found that three specific protein markers—haptoglobin, ceruloplasmin, and blood albumin—were the most predictive of treatment outcomes, achieving a 90.6% effectiveness in prognosis when used together.
Article Abstract
The comprehensive prospective examination of 66 patients with first established non-treated infiltrative tuberculosis of lungs was used to analyze the possibility of optimization of assessment of course of specific inflammatory process on the basis of levels of proteins-reactants of acute phase. The characteristics of dynamics of clinical roentgenologic data and terms of coming of abacillarization as a result of three months anti-tuberculosis therapy has been used as grouping factors. It is established that the constellation of 3 out of 12 basic (before treatment) analyzed level indicators are the most prognostic informative--haptoglobin, ceruloplasmin and blood albumin. Their combined application according the proposed decisive rule provides 90.6% of effectiveness of prognosis of the results of treatment in the discussed category of patients.
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