Population and cytogenetics studies of geographical karyotype changes in East Asiatic mice in East Siberia showed that each population has unique cytogenetic structure, owing to different variants of B-chromosomes system, including 1 to 18 B-chromosomes differing in morphology and size. For each population, we observed the prevalence of mice with a definite number and morphology of B-chromosomes, which is probably the result of homeostatic processes in the population. Local changes were revealed, due to increase in the number of dot-like B-chromosomes in the direction from the West to the East.
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