This study examines the level of knowledge, attitude and practice in matters concerning sexually transmitted diseases (STDs) among secondary school students in Fako-District, Cameroon. A substantial proportion of the respondents are sexually active and doing so with multiple sexual partners. Although 70% of respondents claimed they knew about STDs, not more than 16.1% of them could name any one common STD and give its signs or symptoms. Knowledge about prevention and complications of STDs was equally poor. The school teacher was the principal source of information followed by magazines/books. Among the respondents who had had an STD, only 8% had consulted in an STD clinic, 13.6 and 15.4% respectively to a Doctor and in Hospital, 43% received no treatment and another 19% had gone to chemist shops. The implication of these results together with the needs of the students are discussed.

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