Purpose: To report demographics, wearing patterns, and symptoms from soft contact lens (SCL) wearers with significant SCL-related dryness symptoms with and without significant ocular signs of dryness.
Methods: In a multicenter, prospective observational clinical trial, symptomatic SCL wearers reported significant SCL-related dryness via self-administered questionnaire of frequency and intensity of dryness after a dry eye (DE) examination. DE etiology was assigned post hoc by an expert panel, and those with and without significant DE-related signs were analyzed by univariate logistic regression. Possible DE etiologies were aqueous tear deficiency, SCL-induced tear instability, meibomian gland dysfunction, or "other." Wearers without signs that qualified for any DE etiology were designated as No DE Signs (NDES).
Results: Of the 226 SCL symptomatic wearers examined, 23% were without signs, 30% had aqueous tear deficiency, 25% had SCL-induced tear instability, 14% had meibomian gland dysfunction, and 8% had "other" diagnoses. The NDES wearers had significantly longer pre-lens break-up time (9.8 vs. 6.6 s, p < 0.0001), better lens wetting (3.4 vs. 2.4 0 to 4 scale, p < 0.0001), lower levels of film deposits on lenses (0.45 vs. 0.92, 0 to 4 scale, p < 0.0001), and of most slit lamp signs. The NDES wearers were significantly more likely to be male (36% vs.19%, p = 0.013), were less likely to have deteriorating comfort during the day (81% vs. 97%, p = 0.001), reported longer average hours of comfortable wear (11 ± 3 vs. 9 ± 4 h, p = 0.014), had older contact lenses (18 ± 14 vs. 13 ± 12 days, p = 0.029), and greater intensity of photophobia early and late in the day (p = 0.043 and 0.021).
Conclusions: Symptoms of dryness in SCL wearers stem from a variety of underlying causes. However, nearly one-quarter of these symptomatic SCL wearers appear to be free of signs of dryness. The effective management of CL-related dryness requires a comprehensive range of clinical assessments and the use of a diverse range of management strategies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/OPX.0b013e3182640af8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Translation and validation of the 8-item contact lens dry eye questionnaire (CLDEQ-8) among Chinese soft contact lens wearers.
Cont Lens Anterior Eye
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China. Electronic address:
Purpose: To develop a Chinese version of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) with cross-cultural adaption and clinical validation among soft contact lens wearers (SCL) in China.
Methods: The translation and adaptation of the Chinese CLDEQ-8 (C-CLDEQ-8) followed a rigorous methodological process based on cross-cultural research guidelines consisting of three main phases: 1) forward and backward translation of original CLDEQ-8 into Chinese, 2) cross-cultural adaptation performed by medical advising committee, and 3) clinical validation and repeatability test of the translated questionnaire on Chinese SCL wearers. Rasch analysis was also performed to investigate the psychometric properties of C-CLDEQ-8.
Corneal Endothelial Polymegathism and Pleomorphism Induced by Daily-Wear Soft Contact Lenses.
Cureus
November 2024
Neurology of Vision, Faculty of Optometry and Visual Sciences, Al-Neelain University, Khartoum, SDN.
Background: Corneal endothelium is responsible for maintaining cornea transparency by pumping fluid out of the stroma to prevent the development of corneal edema which leads to blurring of vision.
Purpose: The study aims to investigate the corneal endothelial cell density and morphology in young myopic patients wearing disposable soft contact lenses (SLC) using a non-contact specular biomicroscope.
Methods: A cross-sectional comparative study was conducted at Qassim University's optometry clinics from February to July 2024 in 100 healthy myopic patients, including 100 eyes wearing disposable soft contact lenses and 100 eyes wearing spectacle correction as control group.
A Comparison of Subjective Symptoms of Two Types of Silicone Hydrogel One-Day Disposable Contact Lenses.
Cureus
October 2024
Ophthalmology, Nerima Station West Eye Clinic, Tokyo, JPN.
Purpose: This study aimed to evaluate the comfort and discomfort of two types of soft contact lenses (SCLs) by comparing their quality of vision, fit, subjective dryness, and handling.
Methods: A total of 62 SCL wearers with contact lens (CL) discomfort were recruited. They were fitted with narafilcon A and verofilcon A for two weeks each by crossover.
Experimental Study on Ocular Surface Protection by Soft Contact Lenses Due to Volcanic Ash Exposure.
J Clin Med
September 2024
Shizuoka Research Center for Disaster Medicine, Juntendo University, Izunokuni 410-2295, Japan.
: Sudden volcanic eruptions can lead to volcanic ash entering the eyes, causing severe discomfort and complicating evacuation efforts. The specific effects of volcanic ash on ocular tissues, especially when wearing soft contact lenses (SCLs), are not well documented, prompting this experimental investigation. : White rabbits with normal eyes were randomly divided into three groups: (1) a bare eye group: bare eye + volcanic ash exposure + eye washing, (2) an SCL group: SCL-wearing eye + volcanic ash exposure + eye washing, and (3) a control group: eye washing only.
View Article and Find Full Text PDFThe analysis of tear meniscus parameters during daily soft contact lens wear using optical coherence tomography.
Graefes Arch Clin Exp Ophthalmol
August 2024
Department of Ophthalmology, Tatvan State Hospital, Bitlis, Turkey.
Purpose: To evaluate tear meniscus parameters in soft contact lens wearers (SCL) using optical coherence tomography (OCT) and ImageJ software.
Methods: This prospective study included 50 soft contact lens wearers (group 1: 25 symptomatic SCL wearers (SCLW), group 2: 25 asymptomatic SCL wearers (ASCW)) and 25 healthy non-CL wearers (group 3 (NCLW)). SCLs were fitted on each eye of CL wearers, and the lower tear meniscus was imaged using OCT before CL insertion, immediately afterward, and reimaged 2, 5 and 10 h after insertion.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!