The use of space maintenance in mandibular defects as an interim measure before definitive osseous reconstruction may prevent problems associated with delayed reconstruction including increased technical difficulty, contracture of soft tissues that limits the volume of the final reconstruction, and the potential for iatrogenic injury to adjacent anatomical structures. The use of a condyle/ramus spacer made of medical grade, ultrahigh-molecular-weight polyethylene, and a flexible body spacer made of high quality, inert, non-toxic medical and food grade silicone rubber, was tested in 38 patients with mandibular defects after the resection of benign but locally aggressive disease, advanced osteomyelitis, and injuries. The spacer was retained for a maximum of 8 weeks, and was then removed through an extraoral approach before definitive reconstruction with a particulate corticocancellous bone graft. One of the 38 patients failed to attend for follow up and returned 7 months later with severe, generalised sepsis that required removal of the spacer and exclusion from the study. Of the remaining 37 patients, 32 healed uneventfully, 1 required removal of the spacer 2 weeks after implantation for intraoral wound dehiscence, and 4 had mild to moderate disturbances of wound healing that required either minor revision or local wound care until removal at the time of reconstruction. The use of a spacer promotes wound healing and simplifies and expedites secondary reconstruction of mandibular defects.
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http://dx.doi.org/10.1016/j.bjoms.2012.06.012 | DOI Listing |
Eur Arch Paediatr Dent
January 2025
Department of Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Aim: Pre-eruptive intracoronal resorption (PIER) defects constitute an important part of anomalies associated with unerupted teeth. However, these defects are usually overlooked by clinicians whilst interpreting radiographs. This systematic review was thus orchestrated to find the global prevalence of PEIR.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Department of Plastic Reconstructive and Aesthetic Surgery, Airlangga University-Dr. Soetomo General Hospital Surabaya, Surabaya, East Java.
The spindle cell tumor is a variant of sarcomatoid carcinoma that mostly affects the oral cavity. Bone involvement in this tumor leads to a wide excision, which sometimes requires resection of both the maxilla and mandible. The maxilla and mandible are important bones that function to form the 3-dimensional dimensions of the facial bones.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Resident of Oral and Maxillofacial Radiology, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Early detection of peri-implant bone defects can improve long-term durability of dental implants. By the advances in cone-beam computed tomography (CBCT) scanners and introduction of new algorithms, it is important to find the most efficient protocol for detection of bone defects. This study aimed to assess the efficacy of metal artifact reduction (MAR) and advanced noise reduction (ANR) algorithms for detection of peri-implant bone defects.
View Article and Find Full Text PDFCytotherapy
December 2024
Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Technology Innovation Center of Oral Health, Hebei Medical University & Hebei Key Laboratory of Stomatology & Hebei Clinical Research Center for Oral Diseases, Shijiazhuang, 050017, China. Electronic address:
Objective: This study aimed to evaluate the potential of combining allogeneic adipose-derived mesenchymal stem cells (ADSCs) with autologous concentrated growth factors (CGF) to enhance the repair of mandibular defects in rabbits.
Methods: Rabbit ADSCs were characterized using flow cytometry, identifying CD73, CD90, and CD105 as surface markers, while Alizarin Red Staining confirmed osteogenic differentiation, showing substantial mineralized deposits by day 21. A total of 24 New Zealand white rabbits were divided into four groups: BLANK (control group), CGF, ADSCs, and ADSCs/CGF.
Medicina (Kaunas)
November 2024
Department of oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
Functional rehabilitation in patients with hemimandibulectomy remains a challenge no matter what method of reconstruction is chosen by physicians. In this paper, we aim to evaluate the feasibility of an acceptable occlusal restoration in patients who have undergone hemimanidublectomy without the reestablishment of mandibular continuity. Data were collected retrospectively on 10 patients with varying degrees of mandible resection.
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