One novel compound was isolated from the hexane extract of Choisya ternata Kunth. leaves, choisyaternatine (1), together with the known compounds tecleamaniensine A (2), lup-20(29)-en-3β-ol (lupeol) (3), lup-20(29)-en-3β,24-diol (4), β-sitosterol glucoside (5), and skimmianine (6), plus the following known compounds from the dichloromethane extract, choisyine (7) and 6-methoxy-7,8-methylenedioxycoumarin (8). Compounds 2-5 are reported for the first time in this species. The structures of isolated compounds were elucidated by extensive spectroscopic analyses and comparison with previously reported spectroscopic data. The structure of choisyaternatine was further confirmed based on X-ray data analysis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1055/s-0032-1315044 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antinociceptive activity of puberulin and choisyine from ethanol extract of Choisya ternata Kunth var. Sundance.
Biomed Pharmacother
September 2021
School of Pharmacy and Pharmaceutical Sciences, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. Electronic address:
Article Synopsis
- Choisya ternata Kunth variety Sundance (CTS) is a plant traditionally used in North American medicine, particularly in Mexico, and its antinociceptive properties were evaluated in this study.
- The study found that both the crude ethanolic extract of CTS leaves and its isolated compounds puberulin (Pu) and choisyine (Ch) significantly reduced pain sensitivity in mice when tested with various pain-inducing agents.
- It was revealed that the antinociceptive effects of the CTS extract and Ch could be reversed by an opioid receptor antagonist, while Pu's effects were unaffected; the cholinergic pathway was involved in the actions of CTS extract and Ch, but not with Pu.
Effect of host plant on the life history of the carnation tortrix moth (Lepidoptera: Tortricidae).
Bull Entomol Res
February 2022
Agriculture & Environment Department, Harper Adams University, Newport, ShropshireTF10 8NB, UK.
The carnation tortrix moth, Cacoecimorpha pronubana (Hübner, [1799]) (Lepidoptera: Tortricidae), is one of the most economically important insect species affecting the horticultural industry in the UK. The larvae consume foliage, flowers or fruits, and/or rolls leaves together with silken threads, negatively affecting the growth and/or aesthetics of the crop. In order to understand the polyphagous behaviour of this species within an ornamental crop habitat, we hypothesized that different host plant species affect its life history traits differently.
View Article and Find Full Text PDFIn silico study of the mechanism of action, pharmacokinetic and toxicological properties of some N-methylanthranilates and their analogs.
Food Chem Toxicol
September 2019
School of Pharmacy and Pharmaceutical Sciences, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. Electronic address:
The in silico evaluation for the three previously synthesized compounds (Methyl (MMA), propyl (PMA) and isopropyl (IMA) N-methylanthranilate), MMA and IMA originally found in the leaf essential oil of Choisya ternata, provided a very good confirmation for the in vivo pharmacological results obtained with such compounds for a number of pharmacological targets. This manuscript dealt with their assessment in six pharmacological targets to understanding anti-inflammatory, antinociceptive, anxiolytic, antidepressant and anti-allergic activities using docking molecular as well as their pharmacokinetics and toxicological parameters prediction. The compound IMA seems to be the best one when all the combined parameters are put together.
View Article and Find Full Text PDFDistribution of methyl and isopropyl N-methylanthranilates and their metabolites in organs of rats treated with these two essential-oil constituents.
Food Chem Toxicol
June 2019
University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Višegradska 33, 18000, Niš, Serbia. Electronic address:
Two volatile alkaloids, methyl (MMA) and isopropyl N-methylanthranilates (IMA), identified in the essential oil of Choisya ternata Kunth (Rutaceae), have been proven to possess polypharmacological properties (antinociceptive, anti-inflammatory, gastro-, hepato-, nephroprotective activities, anxiolytic and antidepressant properties, and likewise an effect on diazepam-induced sleep). In the continuation of our investigation of their urinary-metabolite profiles, we performed GC-MS analyses of the diethyl-ether extracts of selected tissues (liver, kidneys, heart, brain, lungs, quadriceps femoris muscle, and spleen) of rats intraperitoneally treated with MMA or IMA (2 g kg). Organ-metabolite profiles of MMA and IMA were qualitatively mutually analogous (varying only in the alcohol moiety of the metabolites), and generally analogous to their urinary-metabolite profiles.
View Article and Find Full Text PDFPhytophthora Species Are Common on Nursery Stock Grown for Restoration and Revegetation Purposes in California.
Plant Dis
March 2019
1 California Department of Food and Agriculture, Plant Pest Diagnostics Center, Sacramento, CA 95832; and.
Phytophthora tentaculata was detected for the first time in North America in 2012 in a nursery on sticky monkeyflower plant (Diplacus aurantiacus) and again in 2014 on outplanted native plants. At that time, this species was listed as a federally actionable and reportable pathogen by the USDA. As a result of these detections, California native plant nurseries were surveyed to determine the prevalence of Phytophthora species on native plant nursery stock.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!