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Brain Dead or Alive: A Case Report of Inaccurate Neurological Prognostication.
Cureus
December 2024
Neurology, Stony Brook University, Stony Brook, USA.
Although numerous definitions of brain death exist, the diagnosis and diagnostic process remain open to interpretation. We present the case of a 32-year-old male with systemic lupus erythematosus who presented to an outside hospital following a cardiac arrest while jogging. His electroencephalogram (EEG) showed abnormal contour in the posterior fields.
View Article and Find Full Text PDFManagement of Recurrent Keratitis as a Complication of Black Scorpion Sting: A Case Report.
Int Med Case Rep J
January 2025
Division of Ophthalmology, Department of Special Surgery, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan.
Scorpions are a group of arthropods known to be highly toxic to humans. We report the case of a previously healthy 61-year-old male who sustained a sting from an Androctonus crassicauda scorpion to his right eye. The patient was admitted to the intensive care unit (ICU) in a comatose state immediately after the sting.
View Article and Find Full Text PDFEfficacy and Renal Safety of Protocol-based 11.7% Hypertonic Saline Infusion Compared with 20% Mannitol in Patients with Elevated Intracranial Pressure: A Study Protocol for a Randomized Clinical Trial.
Electrolyte Blood Press
December 2024
Department of Internal Medicine, College of Medicine, Dankook University, Republic of Korea.
Background: Elevated intracranial pressure (ICP) is a potentially life-threatening condition requiring prompt intervention. While both mannitol and hypertonic saline (HTS) are commonly used hyperosmotic agents for treating elevated ICP, there is insufficient evidence comparing their renal safety profiles and overall effectiveness. This study protocol outlines a pragmatic randomized trial to compare protocol-based 11.
View Article and Find Full Text PDFPrediction of good neurological outcome after return of circulation following paediatric cardiac arrest: A systematic review and meta-analysis.
Resuscitation
December 2024
Department of Critical Care Medicine, Hospital for Sick Children, Department of Paediatrics, University of Toronto, Neurosciences and Mental Health Program, Research Institute Toronto, ON, Canada.
Aim: To evaluate the ability of blood-biomarkers, clinical examination, electrophysiology, or neuroimaging, assessed within 14 days from return of circulation to predict good neurological outcome in children following out- or in-hospital cardiac arrest.
Methods: Medline, EMBASE and Cochrane Trials databases were searched (2010-2023). Sensitivity and false positive rates (FPR) for good neurological outcome (defined as either 'no, mild, moderate disability or minimal change from baseline') in paediatric survivors were calculated for each predictor.
Prognostic factors and impact of management strategies for status epilepticus: The STEPPER study in the Emilia-Romagna region, Italy.
Epilepsia
December 2024
IRCCS Istituto Delle Scienze Neurologiche di Bologna, full member of the European Reference Network for Rare and Complex Epilepsies (EpiCARE), Bologna, Italy.
Objective: The STEPPER (Status Epilepticus in Emilia-Romagna) study aimed to investigate the clinical characteristics, prognostic factors, and treatment approaches of status epilepticus (SE) in adults of the Emilia-Romagna region (ERR), Northern Italy.
Methods: STEPPER, an observational, prospective, multicentric cohort study, was conducted across neurology units, emergency departments, and intensive care units of the ERR over 24 months (October 2019-October 2021), encompassing incident cases of SE. Patients were followed up for 30 days.
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