AI Article Synopsis

  • The study analyzed the impact of serum anti-Mullerian hormone (AMH) levels on ongoing pregnancy rates in women undergoing their first IVF cycle.
  • Data from 1,043 women were categorized into four AMH level groups based on specific cutoff values, with comparisons made between these groups.
  • Results showed a significant correlation between higher serum AMH levels and increased odds of ongoing pregnancy, indicating that AMH levels may be an important factor to consider in IVF treatment outcomes.

Article Abstract

We used logistic regression analysis to investigate the relationship between serum anti-Mullerian hormone (AMH) levels and the rate of ongoing pregnancy. Retrospective data were collected from 1043 women who had undergone their first cycle of in vitro fertilization (IVF), including 540 cycles of fresh embryo transfer and 503 cycles of frozen-thawed embryo transfer. The patients were divided into 4 groups based on the cutoff values from a receiver-operating characteristic curve: 0.0 to 12.4, 12.5 to 25.5, 25.6 to 44.1, and >44.2 pmol/L. After adjustment for multiple confounders, the serum AMH group was found to be significantly related to the rate of ongoing pregnancy in total cycles (0.0-12.4 vs 12.5-25.5 pmol/L; P = .0088, odds ratio, 1.909: vs 25.6-44.1 pmol/L; P = .0281, odds ratio, 2.109: vs >44.2 pmol/L; P = .0008, odds ratio, 2.840). In conclusion, there appears to be a significant relationship between serum AMH levels and the ongoing pregnancy rate in first IVF treatment cycles after adjustment for multiple confounders.

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http://dx.doi.org/10.1177/1933719112450329DOI Listing

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