Poor quality medical care is sometimes attributed to physicians' unwillingness to act on evidence about what works best. Evidence-based performance standards (EBPSs) are one response to this problem, and they are increasingly employed by health care regulators and payers. Evidence in this instance is judged according to the precepts of evidence-based medicine (EBM); it is probabilistic, and the randomized controlled trial (RCT) is the gold standard. This means that EBPSs suffer all the infirmities of EBM generally-well rehearsed problems with the external validity of research findings as well as the inferential leap from study results in the aggregate to individual patient care. These theoretical weaknesses promise to have a practical impact on the care of patients. To avoid this, EBPSs should be understood as guidelines indicative of average effectiveness rather than standards to be applied in every case.
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http://dx.doi.org/10.1007/s11017-012-9226-0 | DOI Listing |
Diabetes Metab Res Rev
January 2025
Faculty of Health and Medical Sciences, Adelaide Medical School, The University of Adelaide, Adelaide, Australia.
Aim: To synthesise the evidence from clinical trials and observational studies using omics techniques to investigate the impact of diet and lifestyle factors on metabolite profile in pregnancy, and in the prevention and management of gestational diabetes mellitus (GDM).
Materials And Methods: A systematic literature search was performed using PubMed, Ovid, CINAHL, and Web of Science databases in October 2023 and updated in September 2024. Inclusion criteria were randomised controlled trials (RCT) or non-RCTs in pregnant women with or without GDM, that measured diet and lifestyle factors, and which applied post-transcriptional omics approaches.
JMIR Med Inform
January 2025
Department of Medical Informatics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Background: The field of digital health solutions (DHS) has grown tremendously over the past years. DHS include tools for self-management, which support individuals to take charge of their own health. The usability of DHS, as experienced by patients, is pivotal to adoption.
View Article and Find Full Text PDFAust J Rural Health
February 2025
The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Objective: To measure current levels and experiences of food and water security in Walgett to guide a community-led program and to provide a baseline measure.
Design: A community-led cross-sectional survey conducted in April 2022 by trained local researchers.
Setting: Walgett, a regional town in NSW, Australia.
Int J Food Sci Nutr
January 2025
Department of Nutrition, School of Public Health, North Khorasan University of Medical Sciences, Bojnurd, Iran.
This meta-analysis aims to compile all randomised controlled trials (RCTs) that examined the effects of grapes or grape products on adult anthropometric measures and serum adipokines. We searched PubMed, Scopus, Google scholar, Web of Science and CENTRAL databases published before January 2022. Random-effects model was used to combine mean differences between intervention and placebo groups.
View Article and Find Full Text PDFUrologie
January 2025
Neuro-Urologie, Schweizer Paraplegiker-Zentrum, Guido A. Zäch-Straße 1, 6207, Nottwil, Schweiz.
A spinal cord injury (SCI) leads to neurogenic lower urinary tract dysfunction (NLUTD), which, if left untreated, can result not only in urinary incontinence and an increased risk of urinary tract infections and kidney dysfunction but may also pose a vital threat to people with SCI. Comprehensive neurourological assessments, including patient history and combined video urodynamics, are essential to accurately classify dysfunction and establish therapeutic strategies. Treatment options include, among others, medications for detrusor regulation, intermittent catheterization, and, if necessary, surgical interventions from intradetrusor botulinum toxin A injections to sacral deafferentation.
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