The technical aspects of wound biocoverage production from the platelets' enriched plasma is represented. The substance shows high regenerative potential by causing the activation of thrombocytic growth factors. The authors' experience of the treatment of 38 patients with chronic trophic ulcers of various etiology is analyzed.
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Fibrin film on clots is increased by haematocrit but reduced by inflammation: implications for platelets and fibrinolysis.
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Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Background: Blood clot formation, triggered by vascular injury, is crucial for haemostasis and thrombosis. Blood clots are composed mainly of fibrin fibres, platelets and red blood cells (RBCs). Recent studies show that clot surface also develops a fibrin film, which provides protection against wound infection and retains components such as RBCs within the clot.
View Article and Find Full Text PDFEffects of (L.) fruit extract on the profile of hematology of ranchu goldfish ().
Open Vet J
November 2024
Department of Pharmacology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Article Synopsis
- The study investigates the effects of calabash fruit extract (BFE) on the growth and blood health of ranchu goldfish, showing that higher concentrations of BFE improve these aspects.
- Group P6, which received the highest BFE concentration, demonstrated the best growth performance and increased levels of specific immune cells (CD4+).
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December 2024
Division of Oral Surgery, Medical University of Gdańsk, 7 Dębinki Street, 80-211 Gdańsk, Poland.
Advanced platelet-rich fibrin (A-PRF) is produced by centrifuging the patient's blood in vacuum tubes for 14 min at 1500 rpm. The most important component of A-PRF is the platelets, which release growth factors from their ⍺-granules during the clotting process. This process is believed to be the main source of growth factors.
View Article and Find Full Text PDFPlatelet stimulation-regulated expression of ILK and ITGB3 contributes to intrahepatic cholangiocarcinoma progression through FAK/PI3K/AKT pathway activation.
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Department of Thoracic Surgery Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
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View Article and Find Full Text PDFRapid Sterilization of Clinical Apheresis Blood Products using Ultra-High Dose Rate Radiation.
bioRxiv
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Stanford Blood Center, Stanford Health Care, Stanford, California, USA.
Background And Objectives: Apheresis platelets products and plasma are essential for medical interventions, but both still have inherent risks associated with contamination and viral transmission. Platelet products are vulnerable to bacterial contamination due to storage conditions, while plasma requires extensive screening to minimize virus transmission risks. Here we investigate rapid irradiation to sterilizing doses for bacteria and viruses as an innovative pathogen reduction technology.
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