Optofluidics integrates the fields of photonics and microfluidics, providing new freedom to both fields and permitting the realization of optical and fluidic property manipulations at the chip scale. Optofluidics was formed only after many breakthroughs in microfluidics, as understanding of fluid behaviour at the micron level enabled researchers to combine the advantages of optics and fluids. This review describes the progress of optofluidics from a photonics perspective, highlighting various optofluidic aspects ranging from the device's property manipulation to an interactive integration between optics and fluids. First, we describe photonic elements based on the functionalities that enable fluid manipulation. We then discuss the applications of optofluidic biodetection with an emphasis on nanosensing. Next, we discuss the progress of optofluidic lenses with an emphasis on its various architectures, and finally we conceptualize on where the field may lead.
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http://dx.doi.org/10.1039/c2lc40467b | DOI Listing |
Eur J Pharm Sci
January 2025
University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia. Electronic address:
Dry eye disease is a multifactorial condition characterized by a loss of homeostasis of the tear film. Among the various treatment approaches, the application of ophthalmic oil-in-water nanoemulsions with incorporated anti-inflammatory drugs represents one of the most advanced approaches. However, the liquid nature of nanoemulsions limits their retention time at the ocular surface.
View Article and Find Full Text PDFSurv Ophthalmol
January 2025
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele-Milan, Italy; Department of Ophthalmology, Eye Unit Humanitas Gavazzeni-Castelli, via Mazzini 11, Bergamo, Italy.
Bacillary layer detachment (BALAD) refers to the distinctive splitting at the level of the photoreceptor inner segment myoid and accumulation of intraretinal fluid, as seen on optical coherence tomography (OCT).BALAD is an increasingly recognized OCT biomarker of numerous heterogeneous chorioretinal diseases, including posterior uveitis, age-related macular degeneration and macular neovascularization, neoplastic and paraneoplastic retinal disorders, rhegmatogenous retinal detachment, blunt ocular trauma, and miscellaneous conditions. The recognition of BALAD is clinically relevant because, based on the specific etiology, BALAD may require simple observation, ocular or systemic medical treatment, or even surgical intervention, with subsequent different prognosis.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Mechanical Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Background: The development of heat transfer devices used for heat conversion and recovery in several industrial and residential applications has long focused on improving heat transfer between two parallel plates. Numerous articles have examined the relevance of enhancing thermal performance for the system's performance and economics. Heat transport is improved by increasing the Reynolds number as the turbulent effects grow.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Key Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.
Lung cancer with heterogeneity has a high mortality rate due to its late-stage detection and chemotherapy resistance. Liquid biopsy that discriminates tumor-related biomarkers in body fluids has emerged as an attractive technique for early-stage and accurate diagnosis. Exosomes, carrying membrane and cytosolic information from original tumor cells, impart themselves endogeneity and heterogeneity, which offer extensive and unique advantages in the field of liquid biopsy for cancer differential diagnosis.
View Article and Find Full Text PDFAdv Mater
January 2025
Institute for Advanced Materials & Guangdong Provincial Key Laboratory of Optical Information Materials and Technology, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, 510006, China.
Laboratory-scale spin-coating techniques are widely employed for fabricating small-size, high-efficiency perovskite solar cells. However, achieving large-area, high-uniformity perovskite films and thus high-efficiency solar cell devices remain challenging due to the complex fluid dynamics and drying behaviors of perovskite precursor solutions during large-area fabrication processes. In this work, a high-quality, pinhole-free, large-area FAPbI perovskite film is successfully obtained via scalable blade-coating technology, assisted by a novel bidirectional Marangoni convection strategy.
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