Aortic stenosis and perioperative risk: the other obstructive defect .

J Heart Valve Dis

Division of Cardiovascular Diseases, Mayo Clinic, 13400 E Shea Blvd., Scottsdale AZ 85255, USA.

Published: May 2012

Whilst the prevalence of aortic valve stenosis (AS) increases with age (1), surgery restores age-corrected survival to near normal. In parallel with senescence, comorbidities are present, one such example being chronic obstructive pulmonary disease (COPD), which causes significant disability and is the third leading cause of death in the United Sates (2). The presence of COPD is associated with increased perioperative complications, and serve as a reason to deny a patient surgical intervention because of the increased surgical risk (3).

Download full-text PDF

Source

Publication Analysis

Top Keywords

aortic stenosis
4
stenosis perioperative
4
perioperative risk
4
risk obstructive
4
obstructive defect
4
defect whilst
4
whilst prevalence
4
prevalence aortic
4
aortic valve
4
valve stenosis
4

Similar Publications

This case report presents the use of intravascular lithotripsy (IVL) in a 68-year-old woman with disabling bilateral claudication owing to a heavily calcified subocclusive stenosis of the infrarenal aorta. The patient had a history of tobacco use, dyslipidemia, and chronic obstructive pulmonary disease, with absent femoral pulses and severe arterial calcification. A 12-mm Shockwave L6 lithotripsy catheter was employed to treat the aortic lesion, resulting in a significant decrease in the aortic pressure gradient without the need for stenting.

View Article and Find Full Text PDF

Background: Epicardial fat tissue (EFT) is an active organ that can affect cardiac function and structure through endocrine, paracrine, and proinflammatory mechanisms. We hypothesized that greater thickness of EFT may harm the recovery of left ventricular (LV) systolic function in patients with severe aortic stenosis (AS) and reduced LV ejection fraction (EF ≤ 50 %) undergoing transcatheter aortic valve implantation (TAVI).

Methods: A sixty six patients with severe AS and 20 % ≥ LVEF ≤ 50 % who underwent TAVI were included.

View Article and Find Full Text PDF

Exploring the Impact of Clonal Hematopoiesis on Heart Failure and Remodeling in Aortic Stenosis.

JACC Adv

February 2025

Division of Cardiology, Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Gyeonggi-do, Republic of Korea.

View Article and Find Full Text PDF

Simultaneous transcatheter aortic valve implantation and femoral osteosynthesis: a case report.

JA Clin Rep

January 2025

Department of Anesthesiology, Japanese Red Cross Kumamoto Hospital, 2-1-1, Nagamine-Minami, Higashi-Ku, Kumamoto, 861-8520, Japan.

Background: Simultaneous cardiac and non-cardiac surgeries can be beneficial for patients, but there are still few reports on this approach.

Case Presentation: A 90-year-old woman was diagnosed with a femoral trochanteric fracture and severe aortic stenosis. A heart team conference decided to perform transcatheter aortic valve implantation (TAVI) and femoral osteosynthesis under general anesthesia on the same day.

View Article and Find Full Text PDF

Subendocardial ischemia: does CMD really exist?

Cardiovasc Revasc Med

January 2025

Weatherhead PET Imaging Center, Division of Cardiology, Department of Medicine, McGovern Medical School at UTHealth and Memorial Hermann Hospital, Houston, TX, United States of America.

Patients with angina but without obstructive epicardial coronary disease still require a specific mechanistic diagnosis to enable targeted treatment. The overarching term "coronary microvascular dysfunction" (CMD) has been applied broadly - but is it correct? We present a series of case examples culminating a systematic exploration of our large clinical database to distinguish among four categories of coronary pathophysiology. First, by far the largest group of "no stenosis angina" patients exhibits subendocardial ischemia during intact flow through diffuse epicardial disease during dipyridamole vasodilator stress.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!