Psychiatric disorders including anxiety disorders, are becoming more and more important in medico-legal assessment. Anxiety disorders are frequent in the general population. However, they may not be reliably diagnosed even by psychiatric experts because the disorders' symptoms may fail to manifest themselves during the examination. Functional impairments related to anxiety disorders are similarly problematic to assess. Finally, given the existence of effective therapies, it is hard to explain why patients with anxiety disorders have to be assessed at all. This report discusses the various and quite heterogeneous concepts associated with the word "anxiety". Anxiety disorder as a disease is differentiated from anxiety as a physiological emotion. Evidence concerning the etiology of anxiety disorders is compiled and strategies for medico-legal assessment, including the efficacy of therapies, are presented.
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Background: Mental health remains among the top 10 leading causes of disease burden globally, and there is a significant treatment gap due to limited resources, stigma, limited accessibility, and low perceived need for treatment. Problem Management Plus, a World Health Organization-endorsed brief psychological intervention for mental health disorders, has been shown to be effective and cost-effective in various countries globally but faces implementation challenges, such as quality control in training, supervision, and delivery. While digital technologies to foster mental health care have the potential to close treatment gaps and address the issues of quality control, their development requires context-specific, interdisciplinary, and participatory approaches to enhance impact and acceptance.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.
Purpose: Major depressive disorder is one of the most common and burdensome psychiatric disorders worldwide. This study evaluated the anxiolytic- and antidepressant-like activity of three semi-synthetic derivatives of xylopic acid (XA) to identify the most promising derivative based on mechanism(s) of action, in vivo pharmacokinetics and in vitro cytotoxicity.
Methods: The anxiolytic potential and the involvement of GABAergic mechanisms were assessed in the elevated plus-maze and open field tests in mice.
J Sleep Res
January 2025
Faculty of Medicine, Damascus University, Damascus, Syria.
A nationwide survey in the USA reported that healthcare workers had the highest prevalence of short sleep duration compared with other professions. Moreover, several studies have reported poor sleep quality among healthcare professionals and described insufficient sleep as a potential driver of reduced physician well-being. This study aims to explore sleep quality and mental health issues among Syrian medical residents, with the goal of informing targeted interventions to enhance their well-being and professional performance.
View Article and Find Full Text PDFJ Dent Sci
January 2025
Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background/purpose: Oral leukoplakia (OLK) and oral lichen planus (OLP) represent two common oral potentially malignant disorders. It would be interesting to know scientific output and characteristics of studies on OLK and OLP.
Materials And Methods: This study aimed to investigate and compare scientometric characteristics of articles on OLK and OLP in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
Ann Neurosci
January 2025
Department of Applied Psychology, GITAM School of Humanities and Social Sciences, Visakhapatnam, Andhra Pradesh, India.
Background: University students confront a wide range of issues during their pursuit of education. Understanding these issues is essential for developing effective treatments and support systems.
Purpose: This study aims to delineate the landscape of scholarly literature pertaining to psychosocial, academic, and psychological issues among university students.
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