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3-Diethyl-carbamoyl-2',4'-difluoro-biphenyl-4-yl 2,6-dichloro-5-fluoro-pyridine-3-carboxyl-ate. | LitMetric

3-Diethyl-carbamoyl-2',4'-difluoro-biphenyl-4-yl 2,6-dichloro-5-fluoro-pyridine-3-carboxyl-ate.

Acta Crystallogr Sect E Struct Rep Online

College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.

Published: July 2012

In the title compound, C(23)H(17)Cl(2)F(3)N(2)O(3), the mol-ecular conformation is significantly strained: atoms O, C(=O) and C attached to the central benzene ring deviate from its plane by 0.118 (2), 0.139 (2) and 0.174 (2) Å, respectively. In the crystal, weak C-H⋯O inter-actions link the mol-ecules into chains along [110]. The crystal packing exhibits short inter-molecular Cl⋯F [2.9840 (16) Å] and Cl⋯Cl [3.2957 (12) Å] contacts.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393315PMC
http://dx.doi.org/10.1107/S1600536812025354DOI Listing

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