Introduction: This investigation aimed to: (1) confirm whether women were more vulnerable to the negative neuromuscular adaptations elicited by muscle unloading and if so, (2) determine which physiological mechanism(s) explain those gender-related differences.
Methods: Healthy young men (20.7 ± 0.3 years) and women (20.3 ± 0.3 years)-(N = 12/group)-participated by completing neuromuscular functional tests before and after 7 days of unloading.
Results: During isokinetic testing of peak torque, work performed, and power, women displayed significantly (P ≤ 0.05) greater declines in performance than men at 1.05 and 2.09, but not 0.53 rads/s. During maximal isometric contractions, women experienced greater strength decrements. Similar gender-specific adaptations to unloading were found in EMG activity, but not muscle mass, neuromuscular transmission, or force relative to EMG.
Conclusions: Women are more susceptible to the adaptations of muscle unloading, and disturbances in neural drive from the central nervous system are probably responsible.
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| http://dx.doi.org/10.1002/mus.23289 | DOI Listing |
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