Visna virus is a retrovirus responsible for a classical slow infection of the central nervous system of sheep. In the present work we focused our attention on the viral mRNA's. We found that, during the acute infection in vitro, (i) viral mRNA's amount to only 0.1% of the total cytoplasmic RNA, (ii) 20% of the total cytoplasmic viral RNA is found in polyribosomes, and (iii) three viral mRNA's can be identified by sucrose gradient sedimentation or polyacrylamide gel electrophoresis. Their sedimentation coefficients are 36S, 27S, and 21S.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC353418PMC
http://dx.doi.org/10.1128/JVI.31.1.25-30.1979DOI Listing

Publication Analysis

Top Keywords

viral mrna's
12
visna virus
8
total cytoplasmic
8
characterization visna
4
virus mrna
4
mrna visna
4
virus retrovirus
4
retrovirus responsible
4
responsible classical
4
classical slow
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!