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Peroxisome proliferator-activated receptors of trophoblast cells in miscarriage. | LitMetric
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Peroxisome proliferator-activated receptors of trophoblast cells in miscarriage.

N V Alexandrova E A Dubova O R Baev A I Shchegolev G T Sukhikh

Bull Exp Biol Med

V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health Care and Social Development of the Russian Federation, Russia.

Published: April 2012

Comparative histological study of uterine curettage specimens in missed abortion in women with spontaneous and induced pregnancy and progressing spontaneous pregnancy revealed similar changes in the endometrium and placental villi. Immunohistochemical assay showed enhanced expression of PPARγ and increased proliferation index (Ki-67) in cells of the villous and extravillous trophoblasts in missed abortion.

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http://dx.doi.org/10.1007/s10517-012-1627-6DOI Listing

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