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A Case of Small-Cell Lung Cancer With Novel Anaplastic Lymphoma Kinase Gene Rearrangement That Developed Intradural Extramedullary Spinal Metastases With Myelitis.
Cureus
December 2024
Department of Neurology, International University of Health and Welfare Narita Hospital, Narita, JPN.
( gene rearrangement-positive small-cell lung cancer (SCLC) is extremely rare. A 73-year-old man was diagnosed with SCLC. Standard treatments were not effective.
View Article and Find Full Text PDFConcurrent Bacteremia and Severe Fever With Thrombocytopenia Syndrome: A Report of Two Cases.
Cureus
December 2024
Department of Emergency and Critical Care Medicine, National Hospital Organization Nagasaki Medical Center, Nagasaki, JPN.
Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne viral hemorrhagic fever caused by the severe fever with thrombocytopenia syndrome virus (SFTSV). This virus, which is transmitted through ticks, is prevalent in Asian countries, including Japan. This report describes two rare cases of SFTS with concurrent bacteremia.
View Article and Find Full Text PDFRemarkable Response to Dabrafenib and Trametinib in a V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) V600E-Mutated Lung Adenocarcinoma Patient With Poor Performance Status and Respiratory Failure: A Case Report.
Cureus
December 2024
Division of Respiratory Medicine, Yuuai Medical Center, Okinawa, JPN.
Article Synopsis
- A 73-year-old man with worsening shortness of breath and respiratory failure was diagnosed with primary lung adenocarcinoma featuring the BRAF V600E mutation after imaging and biopsy.
- He started treatment with a combination of dabrafenib and trametinib, which led to significant clinical and radiological improvements while being well-tolerated despite his critical condition.
- This case highlights the potential effectiveness and safety of targeted therapies for patients with serious health challenges, such as acute respiratory failure and poor performance status, in the context of BRAF V600E mutated non-small cell lung cancer.
Negative-Pressure Wound Therapy: A Novel Approach for Terminal Ileum Anastomosis Success.
Am J Case Rep
January 2025
Department of General Surgery, Fundación Cardioinfantil - LaCardio, Bogotá, Colombia.
BACKGROUND Terminal ileum (TI) anastomoses present challenges due to anatomical features and pressure from the ileocecal valve (ICV). The use of negative-pressure wound therapy (NPWT) is commonly used to treat chronic skin ulcers. Its use for temporary abdominal closure following anastomosis is controversial but has shown promise in patients with inflammatory or vascular disease.
View Article and Find Full Text PDFIntroduction: Laser ablation using a 980-nm wavelength diode laser, which is a new-generation laser, for recurrent bladder cancer is known to have a lower incidence of complications and recurrence than conventional transurethral resection of bladder tumor surgery. This is the first study to report the use of 980-nm diode laser ablation for recurrent non-muscle-invasive bladder cancer in Japan.
Case Presentation: A 73-year-old man underwent transurethral laser ablation for the treatment of recurrent non-muscle-invasive bladder cancer.
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