Seroepidemiological surveillance of Burkholderia pseudomallei in Bangladesh.

Trans R Soc Trop Med Hyg

Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, 3/F, 60th Anniversary Chalermprakiat Bldg, 420/6 Rajvithi Road, Rajathevi, Bangkok 10400, Thailand.

Published: September 2012

Melioidosis (Burkholderia pseudomallei infection) has yet to be demonstrated systematically in Bangladesh. A prospective, cross-sectional serological survey was conducted in 2010 at six Bangladeshi hospitals. Age, gender, occupation and residential address were recorded. Of 1244 patients, 359 (28.9%) were positive for B. pseudomallei by indirect haemagglutination assay. Farmers had an increased risk of seropositivity (risk ratio=1.4, 95% CI 1.0-1.8; p=0.03). There was no clear geographic clustering of seropositives. Melioidosis should be considered as a possible cause of febrile illness in Bangladesh. Further studies are needed to establish the incidence of clinical disease and distribution of environmental risk.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424416PMC
http://dx.doi.org/10.1016/j.trstmh.2012.06.003DOI Listing

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