Melioidosis (Burkholderia pseudomallei infection) has yet to be demonstrated systematically in Bangladesh. A prospective, cross-sectional serological survey was conducted in 2010 at six Bangladeshi hospitals. Age, gender, occupation and residential address were recorded. Of 1244 patients, 359 (28.9%) were positive for B. pseudomallei by indirect haemagglutination assay. Farmers had an increased risk of seropositivity (risk ratio=1.4, 95% CI 1.0-1.8; p=0.03). There was no clear geographic clustering of seropositives. Melioidosis should be considered as a possible cause of febrile illness in Bangladesh. Further studies are needed to establish the incidence of clinical disease and distribution of environmental risk.
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http://dx.doi.org/10.1016/j.trstmh.2012.06.003 | DOI Listing |
Infect Genet Evol
December 2024
University Paris-Est, Anses, Animal health laboratory, Bacterial zoonosis unit, Maisons-Alfort, France. Electronic address:
Burkholderia pseudomallei, a soil-borne bacterium that causes melioidosis, endemic in South and Southeast Asia and northern Australia, is now emerging in new regions. Since the 1990s, cases have been reported in French overseas departments, including Martinique and Guadeloupe in the Caribbean, and Reunion Island and Mayotte in the Indian Ocean, suggesting a local presence of the bacterium. Our phylogenetic analysis of 111 B.
View Article and Find Full Text PDFSouth Afr J Crit Care
July 2024
Department of Critical Care Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Background: Melioidosis cases are increasing in Southeast Asia, posing a significant challenge owing to the rising number of diabetic and immune compromised patients. Pneumonia is the most common presentation of melioidosis, while cutaneous melioidosis is rare.
Objectives: We report a case of primary cutaneous melioidosis (PCM) that eventually required intensive care unit (ICU) management.
Aust Vet J
December 2024
College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia.
Background: Melioidosis, caused by Burkholderia pseudomallei, is an important disease that is endemic in areas of northern Australia and can cause a wide range of clinical signs in people and animals. There is limited published data on the disease in marsupials.
Case Report: Two captive red-legged pademelons (Thylogale stigmatica) with collective signs of lethargy, dysphagia and bloody oral discharge were submitted for necropsy and showed variations in pathology findings ranging from multifocal abscessation in various tissues to evidence of fulminant septicaemia.
PLoS Negl Trop Dis
December 2024
Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America.
Background: Burkholderia pseudomallei, causative agent of melioidosis, is a One Health concern as it is acquired directly from soil and water and causes disease in humans and agricultural and wild animals. We examined B. pseudomallei in soil and goats at a single farm in the Northern Territory of Australia where >30 goats acquired melioidosis over nine years.
View Article and Find Full Text PDFAccess Microbiol
October 2024
Pathology Queensland, Townsville Hospital, Douglas, Townsville, Queensland, Australia.
We report a case of cutaneous melioidosis in a 54-year-old male with a meropenem-resistant sub-population. He was empirically treated with episodic doxycycline and trimethoprim-sulfamethoxazole; however, the abscess re-accumulated. The patient had no prior exposure to meropenem.
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