Introduction: The Raypex 5 is a fourth-generation electronic apex locator for which the accuracy in the presence of chlorhexidine (CHX) and ethylenediaminetetraacetic acid (EDTA) has not yet been tested in vivo. The aim of this in vivo study was to evaluate the performance of the Raypex 5 electronic apex locator in the presence of different irrigant solutions: 2.5% sodium hypochlorite (NaOCl), 2% CHX, and 17% EDTA.
Methods: Thirty-four single-rooted human teeth that were scheduled for extraction were selected for the study. Measurements were performed with the Raypex 5 in the presence of different irrigant solutions: 2.5% NaOCl, 2% CHX, and 17% EDTA. After the teeth were extracted, a #10 K-file was used to determine the reference working length (RWL), which was established to 0.5 mm from the major foramen. The measurements of WL obtained with the different irrigants were compared by analysis of variance. Significance was set at P < .05.
Results: No significant differences were found among the experimental groups (P = .18). The mean distance from the RWL to the file tip was -0.26 ± 1.14 mm when 17% EDTA was used, -0.03 ± 0.92 mm for 2% CHX, and 0.22 ± 0.93 mm for 2.5% NaOCl.
Conclusions: The Raypex 5 performed equally well irrespective of the irrigant used.
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http://dx.doi.org/10.1016/j.joen.2012.05.018 | DOI Listing |
Medicina (Kaunas)
January 2025
Faculty of Dentistry, University of Santiago de Compostela, 15782 Galicia, Spain.
: This systematic review aimed to compare the effect of chitosan in smear layer removal with other commonly used chelators during root canal treatment. : The PRISMA guidelines were followed. Ex vivo studies performed in non-endodontically treated extracted human permanent teeth with a fully formed apex, in which sodium hypochlorite was the main irrigant and chitosan was used as final irrigation to observe its capacity to remove the smear layer using a Scanning Electron Microscope (SEM), were included.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
January 2025
Department of Engineering and Geology, University "G. D'Annunzio" of Chieti-Pescara, Viale Pindaro, Pescara, 65127, Italy. Electronic address:
This study numerically investigates the impact of different loading modes on the biomechanical response of an osseointegrated dental implant. While finite element modeling is commonly employed to investigate the mechanical behavior of dental implants, several models lack physiological accuracy in their loading conditions, omitting occlusal contact points that influence stress distribution in periimplant bone. Using 3D finite element modeling and analysis, stress distributions at the bone-implant interface are evaluated under both physiological loading, incorporating natural occlusal contact points, and non-physiological loading conditions, with a focus on load transmission mechanisms and the potential risk of bone overloading.
View Article and Find Full Text PDFClin Neurol Neurosurg
January 2025
Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium; Department of Neurosciences, Catholic University Leuven, Leuven, Belgium. Electronic address:
Objective: Surgeons routinely check the pupils to assess, in part, the brain stem function and the neural integrity of the visual system. Where a relative afferent pupillary defect is difficult to notice during surgery, an efferent pupillary defect or mydriasis is clearly recognizable. Visual loss in orbital surgery is attributed to compromised perfusion of the optic nerve, retina, or choroid, but an association with mydriasis is generally not assumed.
View Article and Find Full Text PDFCell Rep
January 2025
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA. Electronic address:
Broadly neutralizing antibodies (bNAbs) targeting the apex of the HIV-1-envelope (Env) trimer comprise the most potent category of HIV-1 bNAbs and have emerged as promising therapeutics. Here, we investigate the development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage and report cryo-EM structures at 3.4 Å resolution of PGDM1400 and of an improved PGT145 variant (PGT145-R100aS), each bound to the BG505 Env trimer.
View Article and Find Full Text PDFJ Clin Exp Dent
December 2024
Endodontics, Tehran, Iran.
Background: For a successful root canal treatment, it is necessary to determine the correct working length. One of the most used tools to determine the length is: radiography and apex locator. The accuracy of APEX locator of different generations depends on various factors.
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