Review: metal-based nanoparticles; size, function, and areas for advancement in applied microbiology.

Nanoparticles (NPs) are attracting increased attention in commerce and applied microbiology due to their antimicrobial activity, high electrical conductivity, and optical properties. For example, silver NPs have broad spectrum antimicrobial properties against a wide range of bacteria and fungi, making them ideal for minimizing biofouling. By controlling the size, shape, surface, and agglomeration state of the NPs, specific ion release profiles can be developed for any given application. Currently, NPs are formed in a wide variety of different shapes and sizes including spheres, plates, and wires. This review looks at both commercially and naturally produced NPs with a focus on silver NPs and addresses how these are formed. Furthermore, potential areas for improving these techniques will be highlighted, focusing on advancing shape and structure formation using modern applications. Finally, the review evaluates the feasibility of bioengineering microorganisms to synthesize particles of defined shape and size, by examining genes associated with NP production.