The chronological lifespan (CLS) of budding yeast is a model for the aging of post-mitotic cells in higher eukaryotes. We report here the development of a new method to assess yeast CLS. The new assay is simple, convenient and labor-saving. We applied this new method to screen natural compounds isolated from mushrooms and discovered beauveriolide I as a potent anti-aging agent.
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sp. nov., a novel yeast species isolated from plant leaves in China.
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School of Life Science, Nanyang Normal University, Nanyang 473061, PR China.
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Institute for Synthetic Microbiology, Heinrich Heine University Düsseldorf; Department of Biochemistry and Molecular Biology, Michigan State University.
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Elettra Sincrotrone Trieste, Italy.
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