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This joint practice guideline/procedure standard was collaboratively developed by the European Association of Nuclear Medicine (EANM), the Society of Nuclear Medicine and Molecular Imaging (SNMMI), the European Association of Neuro-Oncology (EANO), and the PET task force of the Response Assessment in Neurooncology Working Group (PET/RANO). Brain metastases are the most common malignant central nervous system (CNS) tumors. PET imaging with radiolabeled amino acids and to lesser extent [F]FDG has gained considerable importance in the assessment of brain metastases, especially for the differential diagnosis between recurrent metastases and treatment-related changes which remains a limitation using conventional MRI.

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SNMMI Procedure Standard/EANM Practice Guideline for Brain [F]FDG PET Imaging, Version 2.0.

J Nucl Med

October 2024

APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Nuclear Medicine Department, Aix Marseille University, Marseille, France.

PREAMBLEThe Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote the science, technology, and practical application of nuclear medicine. The European Association of Nuclear Medicine (EANM) is a professional nonprofit medical association that facilitates communication worldwide between individuals pursuing clinical and research excellence in nuclear medicine. The EANM was founded in 1985.

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EANM/SNMMI guideline/procedure standard for [F]FDG hybrid PET use in infection and inflammation in adults v2.0.

Eur J Nucl Med Mol Imaging

October 2024

Department of Nuclear Medicine, Cliniques Universitaires Saint-Luc and Institute of Clinical and Experimental Research (IREC), Université Catholique de Louvain, Brussels, Belgium.

Article Synopsis
  • - Hybrid [F]FDG PET imaging is the preferred method for diagnosing infectious and inflammatory disorders, with recent updates in clinical guidelines reflecting a surge in evidence-based research since 2013.
  • - The aim of the updated guidelines is to furnish physicians with current, evidence-based knowledge to effectively conduct and interpret hybrid [F]FDG PET scans in adult patients.
  • - A systematic literature review revealed that hybrid [F]FDG PET is highly effective for managing these conditions, although monitoring treatment response remains a challenging area due to limited research.
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Purpose: The recently released EANM/SNMMI guideline, endorsed by several important clinical and imaging societies in the field of breast cancer (BC) care (ACR, ESSO, ESTRO, EUSOBI/ESR, EUSOMA), emphasized the role of [F]FDG PET/CT in management of patients with no special type (NST) BC. This review identifies and summarizes similarities, discrepancies and novelties of the EANM/SNMMI guideline compared to NCCN, ESMO and ABC recommendations.

Methods: The EANM/SNMMI guideline was based on a systematic literature search and the AGREE tool.

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