We report three children with an unusual radiological sign: "trachea with an air fluid level." We suggest this is related to paucity of cough leading to recurrent chest infections. Voluntary cough suppression as a cause of chronic lower respiratory tract infection is recorded in adults (The Lady Windermere Syndrome) but has not previously been reported in children. We propose that in these children impaired airway mucus clearance may be also be caused by voluntary cough suppression. However, the complex physiology of coughing means it is difficult to distinguish between true voluntary cough suppression and paucity of cough due to a subtle neurological deficit. In two patients, the cycle has led to permanent lung damage with bronchiectasis and reduced lung function. In the third, early diagnosis and multidisciplinary intervention has so far delayed progression to bronchiectasis. With greater awareness of this phenomenon in children, there is potential for effective early intervention with medical, physical, and psychological therapies.
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http://dx.doi.org/10.1002/ppul.21623 | DOI Listing |
BMJ Open
January 2025
Clinical and Research Center on Acute Lung Injury, Beijing Shijitan Hospital Capital Medical University, Beijing, Beijing, China
Objectives: The purpose of this study was to evaluate the predictive value of the cough peak flow (CPF) for successful extubation in postcraniotomy critically ill patients.
Design: This was a single-centre prospective diagnostic study.
Setting: The study was conducted in three intensive care units (ICUs) of a teaching hospital.
Am J Transl Res
November 2024
Department of Rehabilitation, Panjin Liao He Oil Field Gem Flower Hospital Panjin 124010, Liaoning, China.
Objective: To investigate the effects of graded exercise rehabilitation training tailored to pulmonary function classification on dyspnea, pulmonary function, and exercise capacity during postoperative rehabilitation in elderly patients following lung cancer surgery.
Methods: A retrospective analysis was conducted on clinical data from 168 elderly patients undergoing postoperative rehabilitation after lung cancer surgery at Panjin Liaohe Oilfield Gem Flower Hospital from January 2021 to December 2022. Patients were divided into two groups based on the rehabilitation received: the control group (n=71), receiving standard rehabilitation, and the study group (n=97), receiving additional graded exercise rehabilitation based on pulmonary function classification.
Immunol Allergy Clin North Am
February 2025
Department of Respiratory Medicine, Thorax Institute, Hospital Maciel, Facultad de Medicina, Universidad de la República, 25 de Mayo 174, Montevideo 11000, Uruguay.
Exercise-induced bronchoconstriction (EIB), a reversible airflow obstruction triggered by exercise, should be considered in patients presenting with symptoms of dyspnea, cough, wheeze, and chest tightness during or after vigorous exercise. Over the past several years, various diagnostic modalities have been developed and evaluated for the diagnosis of EIB, giving the clinician multiple options for diagnostic testing. Here, the authors present a review of the various testing options that can be used in the diagnosis of EIB, with a discussion of testing protocols and considerations for choosing the appropriate diagnostic test.
View Article and Find Full Text PDFGeriatrics (Basel)
October 2024
Department of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
(1) Background: Older adults with chronic stroke may experience compromised upper airway functions due to stroke-related changes and aging. This study aimed to evaluate the functional capacity of the upper airway in older adults with chronic stroke. (2) Methods: A total of 44 patients (22 in each group) were included in the study.
View Article and Find Full Text PDFMov Disord Clin Pract
December 2024
Laboratory for the Study of Upper Airway Dysfunction, Department of Biobehavioral Sciences, Teachers College, Columbia University, New York City, New York, USA.
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