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Background: Overactive bladder (OAB) is an issue in the field of urology that is known for causing symptoms like urges to urinate frequently during the day and even at night (known as nocturia). Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) play a vital role in the growth and operation of nerve cells in the body. New studies are indicating a connection between these neurotrophins and OAB; As such this research project was undertaken to explore how levels of NGT and BDNF in urine might be related to the presence of OAB in individuals.

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Relationship Between Tooth Loss Due to Chronic Periodontitis and Lower Urinary Tract Symptoms.

Medicina (Kaunas)

November 2024

Department of Urology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8501, Japan.

: This study aimed to investigate the relationship between lower urinary tract symptoms (LUTS) and tooth loss due to chronic periodontitis. : A total of 232 patients aged 40 years or older with LUTS were evaluated. The number of remaining teeth and the severity of LUTS were assessed using the overactive bladder symptom score, international prostate symptom score, and urodynamic tests.

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Introduction: Lower urinary tract symptoms (LUTS) are prevalent among older adults, a population that faces multiple medical challenges, with frailty being a major concern. Despite the high prevalence of LUTS, current treatment strategies for older adults are often inadequate. This paper aims to address these issues by defining daytime and/or nighttime LUTS and examining the impact of comorbid conditions on these symptoms.

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Nocturia is defined as the nocturnal frequency of one or more voiding episodes per night. It increases with aging and has an impact on sleep quality and the risks of falling and mortality. Nocturia disorder involves nighttime frequency, nocturnal polyuria, and nocturnal enuresis.

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Article Synopsis
  • Autosomal dominant polycystic kidney disease (ADPKD) is a major hereditary kidney disease, with traditional treatment focusing on symptom management rather than disease progression.
  • Recent advancements in understanding the disease's mechanisms have led to new medications aimed at halting its progression, though their effectiveness for all patients remains uncertain.
  • The review aims to assess the safety and impact of these interventions using patient-focused outcomes while analyzing data from various clinical studies and trials.
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