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| http://dx.doi.org/10.7861/clinmedicine.12-3-207 | DOI Listing |
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Pangenome mining of the Streptomyces genus redefines species' biosynthetic potential.
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The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.
Background: Streptomyces is a highly diverse genus known for the production of secondary or specialized metabolites with a wide range of applications in the medical and agricultural industries. Several thousand complete or nearly complete Streptomyces genome sequences are now available, affording the opportunity to deeply investigate the biosynthetic potential within these organisms and to advance natural product discovery initiatives.
Results: We perform pangenome analysis on 2371 Streptomyces genomes, including approximately 1200 complete assemblies.
Diagnosis of Parkinson's disease by eliciting trait-specific eye movements in multi-visual tasks.
J Transl Med
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School of Information and Communication Engineering, Dalian University of Technology, No. 2 Linggong Road, 116024, Dalian, China.
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View Article and Find Full Text PDFSingle-cell transcriptomics unveils multifaceted immune heterogeneity in early-onset versus late-onset cervical cancer.
World J Surg Oncol
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Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Early-onset (EOCC) and late-onset cervical cancers (LOCC) represent two clinically distinct subtypes, each defined by unique clinical manifestations and therapeutic responses. However, their immunological profiles remain poorly explored. Herein, we analyzed single-cell transcriptomic data from 4 EOCC and 4 LOCC samples to compare their immune architectures.
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The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China.
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World J Surg Oncol
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